| 161 | A Lyth | Yorkshire v Northamptonshire | Headingley, Leeds | 2017 |
| 158* | BB McCullum | Warwickshire v Derbyshire | Edgbaston, Birmingham | 2015 |
| 153* | LJ Wright | Sussex v Essex | The Essex County Ground, Chelmsford | 2014 |
| 152* | GR Napier | Essex v Sussex | The Ford County Ground, Chelmsford | 2008 |
| 151* | CH Gayle | Somerset v Kent | County Ground, Taunton | 2015 |
| 141* | CL White | Somerset v Worcestershire | County Ground, New Road, Worcester | 2006 |
| 139* | JM Cox | Essex v Hampshire | Ambassador Cruise Line Ground, Chelmsford | 2025 |
| 136 | JM Clarke | Nottinghamshire v Northamptonshire | County Ground, Northampton | 2021 |
| 135 | KS Carlson | Glamorgan v Somerset | Sophia Gardens, Cardiff | 2024 |
| 131* | AJ Finch | Surrey v Sussex | The 1st Central County Ground, Hove | 2018 |
| 131 | IR Bell | Warwickshire v Northamptonshire | Edgbaston, Birmingham | 2018 |
| 129 | DT Christian | Middlesex v Kent | Spitfire Ground, St Lawrence, Canterbury | 2014 |
| 129 | CS Delport | Essex v Surrey | The Cloudfm County Ground, Chelmsford | 2019 |
| 129* | JM Vince | Hampshire v Somerset | The Cooper Associates County Ground, Taunton | 2022 |
| 127 | T Kohler-Cadmore | Worcestershire v Durham | County Ground, New Road, Worcester | 2016 |
| 127 | JL Denly | Kent v Essex | The Cloudfm County Ground, Chelmsford | 2017 |
| 126* | M Klinger | Gloucestershire v Essex | County Ground, Bristol | 2015 |
| 124* | MJ Lumb | Hampshire v Essex | The Rose Bowl, Southampton | 2009 |
| 124* | JM Clarke | Worcestershire v Durham | County Ground, New Road, Worcester | 2017 |
| 123 | IA Cockbain | Gloucestershire v Middlesex | Brightside Ground, Bristol | 2018 |
| 122* | JJ Roy | Surrey v Somerset | The Kia Oval, Kennington | 2015 |
| 121* | MM Ali | Worcestershire v Sussex | The 1st Central County Ground, Hove | 2019 |
| 121* | MDE Holden | Middlesex v Kent | Lord's Cricket Ground, St John's Wood | 2023 |
| 120* | JJ Roy | Surrey v Kent | The Kia Oval, Kennington | 2016 |
| 120* | MS Pepper | Essex v Sussex | The 1st Central County Ground, Hove | 2024 |
| 120* | DW Lawrence | Surrey v Glamorgan | The Kia Oval, Kennington | 2025 |
| 119 | KJ O'Brien | Gloucestershire v Middlesex | Uxbridge Cricket Club Ground, Uxbridge | 2011 |
| 119 | AJ Hose | Warwickshire v Northamptonshire | Edgbaston, Birmingham | 2020 |
| 119 | PR Stirling | Warwickshire v Northamptonshire | Edgbaston, Birmingham | 2022 |
| 118 | DJ Willey | Yorkshire v Worcestershire | Headingley, Leeds | 2017 |
| 118* | JP Inglis | Leicestershire v Worcestershire | Uptonsteel County Ground, Leicester | 2021 |
| 118* | LJ Evans | Surrey v Glamorgan | Sophia Gardens, Cardiff | 2023 |
| 117 | MJ Prior | Sussex v Glamorgan | County Ground, Hove | 2010 |
| 117* | AJ Finch | Surrey v Middlesex | The Kia Oval, Kennington | 2018 |
| 117 | DJ Malan | Middlesex v Surrey | The Kia Oval, Kennington | 2019 |
| 116* | GA Hick | Worcestershire v Northamptonshire | Wardown Park, Luton | 2004 |
| 116* | IJ Thomas | Glamorgan v Somerset | County Ground, Taunton | 2004 |
| 116* | CL White | Somerset v Gloucestershire | County Ground, Taunton | 2006 |
| 116* | LJ Wright | Sussex v Hampshire | The Ageas Bowl, Southampton | 2014 |
| 116* | JL Denly | Kent v Surrey | The Kia Oval, Kennington | 2017 |
| 116 | V Chopra | Essex v Kent | The Cloudfm County Ground, Chelmsford | 2017 |
| 116 | JM Bairstow | Yorkshire v Lancashire | Emirates Old Trafford, Manchester | 2025 |
| 115* | DJ Malan | Middlesex v Sussex | The Brighton and Hove Jobs County Ground, Hove | 2015 |
| 115 | MM Ali | Worcestershire v Warwickshire | Edgbaston, Birmingham | 2018 |
| 114 | SA Northeast | Kent v Somerset | County Ground, Taunton | 2015 |
| 114 | CA Ingram | Glamorgan v Essex | The Cloudfm County Ground, Chelmsford | 2017 |
| 114* | AJ Finch | Surrey v Sussex | The Kia Oval, Kennington | 2017 |
| 114* | Babar Azam | Somerset v Glamorgan | Sophia Gardens, Cardiff | 2020 |
| 113* | DT Christian | Nottinghamshire v Northamptonshire | County Ground, Northampton | 2018 |
| 113 | BA Raine | Leicestershire v Warwickshire | Edgbaston, Birmingham | 2018 |
| 113* | CA Lynn | Northamptonshire v Worcestershire | County Ground, Northampton | 2022 |
| 113* | CB Cooke | Glamorgan v Middlesex | Merchant Taylors' School Ground, Northwood | 2023 |
| 112 | A Symonds | Kent v Middlesex | Mote Park, Maidstone | 2004 |
| 112* | CD Nash | Sussex v Somerset | The 1st Central County Ground, Hove | 2016 |
| 112* | DJ Bell-Drummond | Kent v Surrey | The Nevill Ground, Tunbridge Wells | 2016 |
| 112 | JM Bairstow | Yorkshire v Worcestershire | County Ground, New Road, Worcester | 2021 |
| 112* | SR Hain | Warwickshire v Nottinghamshire | Trent Bridge, Nottingham | 2022 |
| 111 | DL Maddy | Leicestershire v Yorkshire | Headingley, Leeds | 2004 |
| 111* | L Klusener | Northamptonshire v Worcestershire | Chester Road North, Kidderminster | 2007 |
| 111 | WJ Durston | Derbyshire v Nottinghamshire | Trent Bridge, Nottingham | 2010 |
| 111* | LJ Wright | Sussex v Gloucestershire | County Ground, Bristol | 2015 |
| 111* | JH Wharton | Yorkshire v Worcestershire | Headingley, Leeds | 2023 |
| 111 | DJ Bell-Drummond | Kent v Middlesex | Spitfire Ground, St Lawrence, Canterbury | 2023 |
| 110 | GA Hick | Worcestershire v Northamptonshire | Chester Road North, Kidderminster | 2007 |
| 110 | J Allenby | Leicestershire v Nottinghamshire | Grace Road, Leicester | 2009 |
| 110* | RE Levi | Northamptonshire v Gloucestershire | College Ground, Cheltenham | 2013 |
| 110 | MH Wessels | Nottinghamshire v Derbyshire | Trent Bridge, Nottingham | 2017 |
| 110 | JL Denly | Kent v Middlesex | Spitfire Ground, St Lawrence, Canterbury | 2022 |
| 110* | AJ Hose | Warwickshire v Worcestershire | Edgbaston, Birmingham | 2022 |
| 110* | SA Abbott | Surrey v Kent | The Kia Oval, Kennington | 2023 |
| 110* | CA Lynn | Northamptonshire v Leicestershire | County Ground, Northampton | 2023 |
| 110* | TA Wood | Derbyshire v Leicestershire | The Incora County Ground, Derby | 2023 |
| 109 | IJ Harvey | Yorkshire v Derbyshire | Headingley, Leeds | 2005 |
| 109* | T Westley | Essex v Sussex | The Essex County Ground, Chelmsford | 2014 |
| 109 | JJ Roy | Surrey v Sussex | The 1st Central County Ground, Hove | 2016 |
| 109* | CS Delport | Leicestershire v Nottinghamshire | Trent Bridge, Nottingham | 2017 |
| 109 | PR Stirling | Middlesex v Surrey | The Kia Oval, Kennington | 2018 |
| 109* | WL Madsen | Derbyshire v Leicestershire | Uptonsteel County Ground, Leicester | 2023 |
| 108* | IJ Harvey | Yorkshire v Lancashire | Headingley, Leeds | 2004 |
| 108* | ME Trescothick | Somerset v Essex | The Ford County Ground, Chelmsford | 2011 |
| 108* | M Klinger | Gloucestershire v Worcestershire | County Ground, Bristol | 2013 |
| 108* | PD Collingwood | Durham v Worcestershire | County Ground, New Road, Worcester | 2017 |
| 108 | KK Jennings | Lancashire v Durham | Emirates Riverside, Chester-le-Street | 2020 |
| 108* | Z Crawley | Kent v Hampshire | The Ageas Bowl, Southampton | 2020 |
| 108 | RS Bopara | Sussex v Kent | Spitfire Ground, St Lawrence, Canterbury | 2023 |
| 107 | ME Trescothick | Somerset v Worcestershire | County Ground, Taunton | 2008 |
| 107* | JC Hildreth | Somerset v Glamorgan | County Ground, Taunton | 2012 |
| 107* | JD Ryder | Essex v Hampshire | The Essex County Ground, Chelmsford | 2015 |
| 107* | JM Vince | Hampshire v Worcestershire | County Ground, New Road, Worcester | 2015 |
| 107* | T Banton | Somerset v Kent | Spitfire Ground, St Lawrence, Canterbury | 2021 |
| 106 | AC Gilchrist | Middlesex v Kent | St Lawrence Ground, Canterbury | 2010 |
| 106* | SB Styris | Essex v Surrey | The Ford County Ground, Chelmsford | 2010 |
| 106* | Azhar Mahmood | Kent v Gloucestershire | The Kent County Cricket Ground, Beckenham | 2011 |
| 106* | CA Lynn | Northamptonshire v Leicestershire | County Ground, Northampton | 2022 |
| 106 | SW Billings | Kent v Somerset | Spitfire Ground, St Lawrence, Canterbury | 2024 |
| 105 | GC Smith | Somerset v Northamptonshire | County Ground, Taunton | 2005 |
| 105 | BF Smith | Worcestershire v Glamorgan | County Ground, New Road, Worcester | 2005 |
| 105* | RS Bopara | Essex v Somerset | The Ford County Ground, Chelmsford | 2010 |
| 105 | J Allenby | Glamorgan v Middlesex | Old Deer Park, Richmond | 2014 |
| 105 | T Westley | Essex v Kent | Castle Park Cricket Ground, Colchester | 2014 |
| 104* | M Klinger | Gloucestershire v Essex | The Essex County Ground, Chelmsford | 2015 |
| 104* | M Klinger | Gloucestershire v Glamorgan | County Ground, Bristol | 2015 |
| 104 | CS MacLeod | Derbyshire v Northamptonshire | County Ground, Northampton | 2018 |
| 104 | RK Patel | Leicestershire v Durham | Uptonsteel County Ground, Leicester | 2023 |
| 104 | RK Patel | Leicestershire v Northamptonshire | County Ground, Northampton | 2024 |
| 104 | TWM Latham | Warwickshire v Derbyshire | The Central Co-op County Ground, Derby | 2025 |
| 103 | LJ Wright | Sussex v Kent | St Lawrence Ground, Canterbury | 2007 |
| 103 | DJ Malan | Middlesex v Lancashire | The Brit Oval, Kennington | 2008 |
| 103 | BJ Hodge | Leicestershire v Nottinghamshire | Grace Road, Leicester | 2010 |
| 103* | AN Petersen | Lancashire v Leicestershire | Fischer County Ground, Grace Road, Leicester | 2016 |
| 103* | V Chopra | Essex v Glamorgan | The Cloudfm County Ground, Chelmsford | 2017 |
| 103* | JG Myburgh | Somerset v Essex | The Cooper Associates County Ground, Taunton | 2018 |
| 103 | JJ Cobb | Northamptonshire v Warwickshire | County Ground, Northampton | 2018 |
| 103* | JP Inglis | Leicestershire v Northamptonshire | County Ground, Northampton | 2021 |
| 103 | JM Vince | Hampshire v Essex | The Cloud County Ground, Chelmsford | 2023 |
| 103 | MM Ali | Warwickshire v Leicestershire | Edgbaston, Birmingham | 2024 |
| 102* | MW Goodwin | Sussex v Essex | The Ford County Ground, Chelmsford | 2007 |
| 102* | L Vincent | Lancashire v Derbyshire | Old Trafford, Manchester | 2008 |
| 102 | RN ten Doeschate | Essex v Middlesex | Lord's Cricket Ground, St John's Wood | 2010 |
| 102 | HJH Marshall | Gloucestershire v Middlesex | Uxbridge Cricket Club Ground, Uxbridge | 2011 |
| 102 | GP Smith | Leicestershire v Nottinghamshire | Grace Road, Leicester | 2014 |
| 102* | JM Bairstow | Yorkshire v Durham | Emirates Durham International Cricket Ground, Chester-le-Street | 2014 |
| 102 | JL Denly | Kent v Surrey | The Kia Oval, Kennington | 2018 |
| 102 | MJ Guptill | Worcestershire v Northamptonshire | County Ground, Northampton | 2018 |
| 102* | CJ Ferguson | Worcestershire v Nottinghamshire | Trent Bridge, Nottingham | 2018 |
| 102* | Babar Azam | Somerset v Hampshire | The Ageas Bowl, Southampton | 2019 |
| 102* | AJ Finch | Surrey v Somerset | The Kia Oval, Kennington | 2019 |
| 102* | M Klinger | Gloucestershire v Kent | Spitfire Ground, St Lawrence, Canterbury | 2019 |
| 102* | MDE Holden | Middlesex v Essex | The Cloudfm County Ground, Chelmsford | 2020 |
| 102* | SS Eskinazi | Middlesex v Essex | Lord's Cricket Ground, St John's Wood | 2021 |
| 102 | JM Vince | Hampshire v Sussex | The Ageas Bowl, Southampton | 2021 |
| 102* | G Clark | Durham v Northamptonshire | County Ground, Northampton | 2023 |
| 102* | SM Curran | Surrey v Hampshire | The Kia Oval, Kennington | 2024 |
| 101 | SG Law | Lancashire v Yorkshire | Old Trafford, Manchester | 2005 |
| 101* | JHK Adams | Hampshire v Surrey | The Rose Bowl, Southampton | 2010 |
| 101* | JJ Roy | Surrey v Kent | The Kent County Cricket Ground, Beckenham | 2010 |
| 101* | HH Gibbs | Yorkshire v Northamptonshire | County Ground, Northampton | 2010 |
| 101* | JA Rudolph | Glamorgan v Gloucestershire | County Ground, Bristol | 2015 |
| 101 | M Klinger | Gloucestershire v Somerset | The Cooper Associates County Ground, Taunton | 2016 |
| 101 | CA Ingram | Glamorgan v Essex | The Essex County Ground, Chelmsford | 2016 |
| 101* | CA Ingram | Glamorgan v Sussex | Arundel Castle Cricket Club Ground, Arundel | 2017 |
| 101 | LJ Wright | Sussex v Glamorgan | Arundel Castle Cricket Club Ground, Arundel | 2017 |
| 101* | M Klinger | Gloucestershire v Hampshire | Brightside Ground, Bristol | 2017 |
| 101 | AD Hales | Nottinghamshire v Yorkshire | Trent Bridge, Nottingham | 2017 |
| 101 | Shahid Afridi | Hampshire v Derbyshire | The 3aaa County Ground, Derby | 2017 |
| 101* | TB Abell | Somerset v Middlesex | The Cooper Associates County Ground, Taunton | 2019 |
| 101* | AD Hales | Nottinghamshire v Lancashire | Trent Bridge, Nottingham | 2021 |
| 101 | SJ Croft | Lancashire v Northamptonshire | County Ground, Northampton | 2023 |
| 101 | MS Pepper | Essex v Middlesex | The Cloud County Ground, Chelmsford | 2024 |
| 101* | AZ Lees | Durham v Northamptonshire | Banks Homes Riverside, Chester-le-Street | 2025 |
| 100* | IJ Harvey | Gloucestershire v Warwickshire | Edgbaston, Birmingham | 2003 |
| 100 | MB Loye | Lancashire v Durham | Old Trafford, Manchester | 2005 |
| 100* | RC Irani | Essex v Sussex | County Ground, Hove | 2006 |
| 100 | HJH Marshall | Gloucestershire v Worcestershire | Chester Road North, Kidderminster | 2007 |
| 100* | GM Smith | Derbyshire v Yorkshire | Headingley, Leeds | 2008 |
| 100 | VS Solanki | Worcestershire v Glamorgan | County Ground, New Road, Worcester | 2009 |
| 100* | AN Cook | Essex v Surrey | The Brit Oval, Kennington | 2009 |
| 100* | JHK Adams | Hampshire v Glamorgan | The Rose Bowl, Southampton | 2010 |
| 100* | MW Goodwin | Sussex v Surrey | The PROBIZ County Ground, Hove | 2011 |
| 100* | SB Styris | Sussex v Gloucestershire | The PROBIZ County Ground, Hove | 2012 |
| 100* | MA Carberry | Hampshire v Lancashire | The Ageas Bowl, Southampton | 2013 |
| 100 | DJ Willey | Northamptonshire v Sussex | The Brighton and Hove Jobs County Ground, Hove | 2015 |
| 100 | LS Livingstone | Lancashire v Derbyshire | The 3aaa County Ground, Derby | 2018 |
| 100 | T Banton | Somerset v Kent | The Cooper Associates County Ground, Taunton | 2019 |
| 100* | JM Clarke | Nottinghamshire v Durham | Emirates Riverside, Chester-le-Street | 2020 |
| 100 | HD Rutherford | Worcestershire v Glamorgan | Blackfinch New Road, Worcester | 2020 |
| 100* | TL Seifert | Sussex v Hampshire | The Ageas Bowl, Southampton | 2022 |
| 100 | JM Vince | Hampshire v Kent | The Ageas Bowl, Southampton | 2022 |
| 100* | WL Madsen | Derbyshire v Durham | The Incora County Ground, Derby | 2022 |
| 100 | DJ Bell-Drummond | Kent v Somerset | The Cooper Associates County Ground, Taunton | 2025 |
| 100 | TS Muyeye | Kent v Essex | Ambassador Cruise Line Ground, Chelmsford | 2025 |
| 100 | WG Jacks | Surrey v Sussex | The 1st Central County Ground, Hove | 2025 |
