| Runs |
Out of |
4s |
6s |
| 110 | 132 | 20 | 5 | | HK Matthews | West Indies Women v Australia Women | North Sydney Oval, Sydney | 2023/24 |
| 68 | 85* | 17 | 0 | | HK Matthews | West Indies Women v India Women | Dr DY Patil Sports Academy, Mumbai | 2024/25 |
| 70 | 100* | 16 | 1 | | HK Matthews | West Indies Women v England Women | Spitfire Ground, St Lawrence, Canterbury | 2025 |
| 82 | 112* | 7 | 9 | | DJS Dottin | West Indies Women v South Africa Women | Warner Park, Basseterre | 2010 |
| 82 | 107* | 7 | 9 | | HK Matthews | West Indies Women v Ireland Women | Sydney Parade, Dublin | 2019 |
| 72 | 99* | 12 | 4 | | HK Matthews | West Indies Women v Australia Women | North Sydney Oval, Sydney | 2023/24 |
| 66 | 90 | 12 | 3 | | SR Taylor | West Indies Women v India Women | Dr Gokaraju Liala Gangaaraju Andhra Cricket Association Cricket Ground, Mulapadu | 2016/17 |
| 68 | 79 | 11 | 4 | | HK Matthews | West Indies Women v Australia Women | Allan Border Field, Brisbane | 2023/24 |
| 60 | 90 | 12 | 2 | | SR Taylor | West Indies Women v Ireland Women | Kenure, Rush, Dublin | 2008 |
| 66 | 112 | 9 | 5 | | DJS Dottin | West Indies Women v Sri Lanka Women | Coolidge Cricket Ground, Coolidge | 2017/18 |
| 48 | 81 | 12 | 0 | | SC King | West Indies Women v Netherlands Women | Absa Puk Oval, Potchefstroom | 2010/11 |
| 50 | 78 | 11 | 1 | | SR Taylor | West Indies Women v Australia Women | Melbourne Cricket Ground, Melbourne | 2014/15 |
| 56 | 90* | 8 | 4 | | DJS Dottin | West Indies Women v Pakistan Women | Southend Club Cricket Stadium, Karachi | 2018/19 |
| 50 | 75 | 11 | 1 | | SR Taylor | West Indies Women v Ireland Women | Claremont Road, Dublin | 2019 |
| 50 | 71 | 11 | 1 | | HK Matthews | West Indies Women v England Women | Ambassador Cruise Line Ground, Chelmsford | 2025 |
| 52 | 75 | 7 | 4 | | SR Taylor | West Indies Women v Sri Lanka Women | R Premadasa Stadium, Colombo | 2012/13 |
| 50 | 70 | 8 | 3 | | HK Matthews | West Indies Women v South Africa Women | Brian Lara Stadium, Tarouba | 2018/19 |
| 44 | 59 | 11 | 0 | | SR Taylor | West Indies Women v Australia Women | North Sydney Oval, Sydney | 2023/24 |
| 44 | 78 | 11 | 0 | | HK Matthews | West Indies Women v Pakistan Women | National Bank Cricket Arena, Karachi | 2023/24 |
| 48 | 63 | 9 | 2 | | Q Joseph | West Indies Women v Bangladesh Women | Warner Park, Basseterre | 2024/25 |
| 42 | 53 | 9 | 1 | | DJS Dottin | West Indies Women v Australia Women | County Ground, Taunton | 2009 |
| 40 | 53 | 10 | 0 | | HK Matthews | West Indies Women v New Zealand Women | Bay Oval, Mount Maunganui | 2017/18 |
| 44 | 62 | 8 | 2 | | HK Matthews | West Indies Women v Sri Lanka Women | Daren Sammy National Cricket Stadium, Gros Islet | 2018/19 |
| 42 | 63 | 9 | 1 | | DJS Dottin | West Indies Women v England Women | The Incora County Ground, Derby | 2020 |
| 40 | 58 | 10 | 0 | | HK Matthews | West Indies Women v Pakistan Women | National Bank Cricket Arena, Karachi | 2023/24 |
| 40 | 68 | 10 | 0 | | HK Matthews | West Indies Women v Pakistan Women | National Bank Cricket Arena, Karachi | 2023/24 |
| 42 | 65 | 9 | 1 | | HK Matthews | West Indies Women v South Africa Women | Three Ws Oval, Cave Hill | 2025 |
| 40 | 57 | 7 | 2 | | DJS Dottin | West Indies Women v India Women | Sylhet Stadium, Sylhet | 2013/14 |
| 42 | 66 | 6 | 3 | | HK Matthews | West Indies Women v Australia Women | Eden Gardens, Kolkata | 2015/16 |
| 38 | 66* | 8 | 1 | | HK Matthews | West Indies Women v Ireland Women | PPC Newlands, Cape Town | 2022/23 |
| 36 | 50 | 9 | 0 | | HK Matthews | West Indies Women v Ireland Women | Daren Sammy National Cricket Stadium, Gros Islet | 2023 |
