| 151* | JP Greaves | v Trinidad and Tobago | Brian Lara Stadium, Tarouba | 2024/25 | a31239 |
| 145* | EA Lewis | v Barbados | Kensington Oval, Bridgetown | 1984/85 | a4310 |
| 141 | ACL Richards | v Canada | Everest Cricket Club Ground, Georgetown | 2008/09 | a19219 |
| 135 | KOA Powell | v Windward Islands | Coolidge Cricket Ground, Coolidge | 2016/17 | a25115 |
| 132* | RRS Cornwall | v United States of America | Coolidge Cricket Ground, Coolidge | 2017/18 | a25973 |
| 126 | WW Cornwall | v United States of America | Kensington Park, Kingston | 1998/99 | a11413 |
| 125* | RRS Cornwall | v United States of America | Three Ws Oval, Cave Hill | 2018/19 | a26839 |
| 123* | KU Carty | v Barbados | Coolidge Cricket Ground, Coolidge | 2020/21 | a28146 |
| 121* | KOA Powell | v Jamaica | Conaree Sports Club, Conaree | 2019/20 | a27755 |
| 121 | JP Greaves | v Windward Islands | Queen's Park Oval, Port of Spain | 2023/24 | a30348 |
| 119 | RRS Cornwall | v Guyana | Coolidge Cricket Ground, Coolidge | 2017/18 | a25997 |
| 118 | KLT Arthurton | v Jamaica | Kaiser Sports Club, Discovery Bay | 1996/97 | a10091 |
| 117 | DC Thomas | v Barbados | Sir Vivian Richards Stadium, North Sound | 2020/21 | a28238 |
| 113* | RRS Cornwall | v West Indies Under-19s | National Cricket Centre, Couva | 2014/15 | a23919 |
| 112 | NR Kumar | v Windward Islands | Coolidge Cricket Ground, Coolidge | 2020/21 | a28144 |
| 112 | JP Greaves | v Barbados | Queen's Park Oval, Port of Spain | 2024/25 | a31229 |
| 111* | JP Greaves | v West Indies Academy | Queen's Park Oval, Port of Spain | 2024/25 | a31224 |
| 106 | KOA Powell | v Kent | Coolidge Cricket Ground, Coolidge | 2016/17 | a25138 |
| 106* | MN Samuels | v Jamaica | Coolidge Cricket Ground, Coolidge | 2017/18 | a25983 |
| 105 | SC Williams | v Jamaica | Antigua Recreation Ground, St John's | 1992/93 | a7955 |
| 105 | KOA Powell | v West Indies Under-19s | Sir Vivian Richards Stadium, North Sound | 2016/17 | a25105 |
| 105 | DC Thomas | v Combined Campuses and Colleges | Warner Park, Basseterre | 2019/20 | a27743 |
| 105 | KOA Powell | v Jamaica | Conaree Sports Club, Conaree | 2019/20 | a27817 |
| 103* | KLT Arthurton | v Barbados | Albion Sports Complex, Albion | 1997/98 | a10736 |
| 103* | DC Thomas | v Guyana | Coolidge Cricket Ground, Coolidge | 2017/18 | a26139 |
| 103* | KU Carty | v West Indies Emerging Players | Sir Vivian Richards Stadium, North Sound | 2022/23 | a29472 |
| 101* | RS Morton | v Jamaica | Uitvlugt Community Centre Ground, Uitvlugt | 2004/05 | a16193 |
| 100 | KLT Arthurton | v Guyana | Kaiser Sports Club, Discovery Bay | 1997/98 | a10762 |
| 100* | SC Joseph | v Jamaica | Kaiser Sports Club, Discovery Bay | 1999/00 | a12247 |
| 100* | SC Joseph | v Jamaica | St Mary's Park, Cayon | 2006/07 | a17850 |
| 100 | SM Jeffers | v Guyana | Albion Sports Complex, Albion | 2006/07 | a17916 |
