| Runs |
Out of |
4s |
6s |
| 36 | 47* | 9 | 0 | | EH Rendler | United States of America Women v Canada Women | Central Broward Regional Park Stadium Turf Ground, Lauderhill | 2019 |
| 36 | 57 | 9 | 0 | | D Dhingra | United States of America Women v Zimbabwe Women | Grand Prairie Stadium, Grand Prairie | 2025 |
| 32 | 74* | 8 | 0 | | S Sriharsha | United States of America Women v Bangladesh Women | Sheikh Zayed Stadium, Abu Dhabi | 2022 |
| 32 | 60* | 8 | 0 | | AI Chudasama | United States of America Women v Netherlands Women | Sportpark Maarschalkerweerd, Utrecht | 2025 |
| 24 | 38 | 6 | 0 | | S Sriharsha | United States of America Women v Canada Women | Central Broward Regional Park Stadium Turf Ground, Lauderhill | 2019 |
| 24 | 30 | 6 | 0 | | SM Bhaskar | United States of America Women v Canada Women | Central Broward Regional Park Stadium Turf Ground, Lauderhill | 2019 |
| 24 | 53* | 6 | 0 | | NT Gruny | United States of America Women v Netherlands Women | Lochlands Park, Arbroath | 2019 |
| 24 | 58 | 6 | 0 | | D Dhingra | United States of America Women v Canada Women | Woodley Cricket Field, Los Angeles | 2023 |
| 24 | 35 | 3 | 2 | | EH Rendler | United States of America Women v Papua New Guinea Women | Lochlands Park, Arbroath | 2019 |
| 20 | 39* | 5 | 0 | | GC Bhogle | United States of America Women v Canada Women | Reforma Athletic Club, Naucalpan | 2021/22 |
| 20 | 50* | 5 | 0 | | S Sriharsha | United States of America Women v Thailand Women | ICC Cricket Academy Ground, Dubai | 2022 |
| 20 | 23 | 5 | 0 | | M Kandanala | United States of America Women v United Arab Emirates Women | ICC Cricket Academy Ground, Dubai | 2022 |
| 20 | 48* | 5 | 0 | | L Ramjit | United States of America Women v United Arab Emirates Women | Tolerance Oval, Abu Dhabi | 2022 |
| 26 | 37 | 2 | 3 | | RP Singh | United States of America Women v Canada Women | Woodley Cricket Field, Los Angeles | 2023 |
| 18 | 42* | 3 | 1 | | S Sriharsha | United States of America Women v Canada Women | Central Broward Regional Park Stadium Turf Ground, Lauderhill | 2019 |
| 16 | 33 | 4 | 0 | | NT Gruny | United States of America Women v Namibia Women | Lochlands Park, Arbroath | 2019 |
| 16 | 27 | 4 | 0 | | L Ramjit | United States of America Women v United Arab Emirates Women | ICC Cricket Academy Ground, Dubai | 2022 |
| 16 | 63* | 4 | 0 | | D Dhingra | United States of America Women v Argentina Women | Woodley Cricket Field, Los Angeles | 2023 |
| 16 | 52* | 4 | 0 | | S Sriharsha | United States of America Women v Brazil Women | Woodley Cricket Field, Los Angeles | 2023 |
| 16 | 26* | 4 | 0 | | GC Bhogle | United States of America Women v Brazil Women | Woodley Cricket Field, Los Angeles | 2023 |
| 16 | 28 | 4 | 0 | | D Dhingra | United States of America Women v Sri Lanka Women | Tolerance Oval, Abu Dhabi | 2024 |
| 16 | 25 | 4 | 0 | | CR Pagydyala | United States of America Women v Zimbabwe Women | Grand Prairie Stadium, Grand Prairie | 2025 |
| 18 | 34 | 3 | 1 | | GC Bhogle | United States of America Women v Zimbabwe Women | Grand Prairie Stadium, Grand Prairie | 2025 |
| 12 | 23* | 3 | 0 | | SM Bhaskar | United States of America Women v Argentina Women | Reforma Athletic Club, Naucalpan | 2021/22 |
| 12 | 21 | 3 | 0 | | S Sriharsha | United States of America Women v Zimbabwe Women | ICC Cricket Academy Ground, Dubai | 2022 |
| 12 | 25 | 3 | 0 | | S Sriharsha | United States of America Women v Ireland Women | Tolerance Oval, Abu Dhabi | 2022 |
| 12 | 26 | 3 | 0 | | S Sriharsha | United States of America Women v United Arab Emirates Women | Tolerance Oval, Abu Dhabi | 2022 |
| 12 | 20 | 3 | 0 | | A Kolan | United States of America Women v Canada Women | Woodley Cricket Field, Los Angeles | 2023 |
| 12 | 24 | 3 | 0 | | S Sriharsha | United States of America Women v Canada Women | Woodley Cricket Field, Los Angeles | 2023 |
| 12 | 48 | 3 | 0 | | A Kolan | United States of America Women v Argentina Women | Woodley Cricket Field, Los Angeles | 2023 |
| 12 | 13 | 3 | 0 | | P Ganesh | United States of America Women v Thailand Women | Sheikh Zayed Stadium, Abu Dhabi | 2024 |
| 12 | 27 | 3 | 0 | | S Sriharsha | United States of America Women v Sri Lanka Women | Tolerance Oval, Abu Dhabi | 2024 |
| 14 | 39 | 2 | 1 | | EC Claridge | United States of America Women v Brazil Women | St Albans Club, Buenos Aires | 2024/25 |
| 12 | 20 | 3 | 0 | | EC Claridge | United States of America Women v Canada Women | St Albans Club, Buenos Aires | 2024/25 |
| 12 | 25 | 3 | 0 | | CR Pagydyala | United States of America Women v Zimbabwe Women | Grand Prairie Stadium, Grand Prairie | 2025 |
| 12 | 15 | 3 | 0 | | CR Pagydyala | United States of America Women v Netherlands Women | Sportpark Maarschalkerweerd, Utrecht | 2025 |
