| Runs |
Wkts |
| 398 | 11 | Sydney Sixers Women v Melbourne Stars Women | North Sydney Oval, Sydney | 2017/18 |
| 362 | 9 | Sydney Sixers Women v Melbourne Stars Women | North Sydney Oval, Sydney | 2020/21 |
| 357 | 15 | Melbourne Renegades Women v Sydney Sixers Women | Adelaide Oval, Adelaide | 2024/25 |
| 356 | 8 | Perth Scorchers Women v Sydney Sixers Women | St Kilda Cricket Ground, Melbourne | 2022/23 |
| 353 | 6 | Melbourne Stars Women v Sydney Sixers Women | Western Australia Cricket Association West Ground, Perth | 2019/20 |
| 353 | 11 | Brisbane Heat Women v Sydney Sixers Women | Allan Border Field, Brisbane | 2023/24 |
| 345 | 10 | Brisbane Heat Women v Sydney Sixers Women | Aquinas College Memorial Oval, Perth | 2015/16 |
| 341 | 14 | Sydney Sixers Women v Adelaide Strikers Women | Hurstville Oval, Sydney | 2019/20 |
| 339 | 12 | Melbourne Renegades Women v Sydney Sixers Women | Eastern Oval, Ballarat | 2022/23 |
| 338 | 13 | Sydney Sixers Women v Perth Scorchers Women | North Sydney Oval, Sydney | 2018/19 |
| 338 | 11 | Sydney Sixers Women v Adelaide Strikers Women | Hurstville Oval, Sydney | 2018/19 |
| 338 | 13 | Sydney Sixers Women v Sydney Thunder Women | North Sydney Oval, Sydney | 2022/23 |
| 338 | 14 | Sydney Sixers Women v Sydney Thunder Women | North Sydney Oval, Sydney | 2023/24 |
| 335 | 15 | Sydney Sixers Women v Sydney Thunder Women | North Sydney Oval, Sydney | 2019/20 |
| 335 | 8 | Sydney Sixers Women v Melbourne Renegades Women | North Sydney Oval, Sydney | 2020/21 |
| 334 | 12 | Perth Scorchers Women v Sydney Sixers Women | Lilac Hill Park, Perth | 2018/19 |
| 331 | 10 | Melbourne Stars Women v Sydney Sixers Women | St Kilda Cricket Ground, Melbourne | 2018/19 |
| 331 | 19 | Sydney Sixers Women v Adelaide Strikers Women | North Sydney Oval, Sydney | 2024/25 |
| 330 | 9 | Sydney Sixers Women v Perth Scorchers Women | Hurstville Oval, Sydney | 2020/21 |
| 329 | 8 | Perth Scorchers Women v Sydney Sixers Women | Lilac Hill Park, Perth | 2019/20 |
| 328 | 17 | Sydney Sixers Women v Melbourne Stars Women | North Sydney Oval, Sydney | 2023/24 |
| 327 | 10 | Sydney Sixers Women v Brisbane Heat Women | North Sydney Oval, Sydney | 2022/23 |
| 323 | 15 | Sydney Sixers Women v Sydney Thunder Women | Sydney Cricket Ground, Sydney | 2015/16 |
| 322 | 16 | Melbourne Renegades Women v Sydney Sixers Women | St Kilda Cricket Ground, Melbourne | 2023/24 |
| 321 | 10 | Sydney Sixers Women v Brisbane Heat Women | Sydney Cricket Ground, Sydney | 2018/19 |
| 321 | 4 | Brisbane Heat Women v Sydney Sixers Women | Karen Rolton Oval, Adelaide | 2021/22 |
| 317 | 16 | Sydney Sixers Women v Perth Scorchers Women | North Sydney Oval, Sydney | 2023/24 |
| 313 | 6 | Perth Scorchers Women v Sydney Sixers Women | Lilac Hill Park, Perth | 2022/23 |
| 313 | 12 | Sydney Sixers Women v Hobart Hurricanes Women | North Sydney Oval, Sydney | 2022/23 |
| 311 | 15 | Sydney Sixers Women v Brisbane Heat Women | Sydney Cricket Ground, Sydney | 2017/18 |
| 311 | 13 | Sydney Thunder Women v Sydney Sixers Women | North Sydney Oval, Sydney | 2022/23 |
