| Runs |
Out of |
4s |
6s |
| 96 | 111 | 15 | 6 | | AJ Healy | Sydney Sixers Women v Melbourne Stars Women | North Sydney Oval, Sydney | 2020/21 |
| 96 | 114 | 9 | 10 | | AK Gardner | Sydney Sixers Women v Melbourne Stars Women | North Sydney Oval, Sydney | 2017/18 |
| 80 | 112* | 17 | 2 | | AJ Healy | Sydney Sixers Women v Adelaide Strikers Women | Hurstville Oval, Sydney | 2018/19 |
| 76 | 106* | 13 | 4 | | AJ Healy | Sydney Sixers Women v Melbourne Stars Women | Western Australia Cricket Association West Ground, Perth | 2019/20 |
| 70 | 106 | 13 | 3 | | AJ Healy | Sydney Sixers Women v Adelaide Strikers Women | Hurstville Oval, Sydney | 2017/18 |
| 68 | 102* | 14 | 2 | | EA Perry | Sydney Sixers Women v Perth Scorchers Women | North Sydney Oval, Sydney | 2018/19 |
| 72 | 107* | 12 | 4 | | AJ Healy | Sydney Sixers Women v Perth Scorchers Women | St Kilda Cricket Ground, Melbourne | 2022/23 |
| 66 | 79* | 12 | 3 | | AK Gardner | Sydney Sixers Women v Hobart Hurricanes Women | Blundstone Arena, Hobart | 2018/19 |
| 70 | 103* | 10 | 5 | | EA Perry | Sydney Sixers Women v Brisbane Heat Women | Sydney Cricket Ground, Sydney | 2018/19 |
| 58 | 81 | 13 | 1 | | EA Perry | Sydney Sixers Women v Sydney Thunder Women | North Sydney Oval, Sydney | 2019/20 |
| 70 | 84 | 7 | 7 | | AJ Healy | Sydney Sixers Women v Adelaide Strikers Women | Hurstville Oval, Sydney | 2019/20 |
| 60 | 94* | 12 | 2 | | AJ Healy | Sydney Sixers Women v Perth Scorchers Women | Lilac Hill Park, Perth | 2021/22 |
| 64 | 85 | 10 | 4 | | AK Gardner | Sydney Sixers Women v Sydney Thunder Women | North Sydney Oval, Sydney | 2022/23 |
| 62 | 81 | 11 | 3 | | EA Perry | Sydney Sixers Women v Melbourne Renegades Women | Adelaide Oval, Adelaide | 2024/25 |
| 60 | 91* | 9 | 4 | | EA Perry | Sydney Sixers Women v Melbourne Stars Women | North Sydney Oval, Sydney | 2017/18 |
| 58 | 82* | 10 | 3 | | EA Perry | Sydney Sixers Women v Sydney Thunder Women | Sydney Cricket Ground, Sydney | 2023/24 |
| 56 | 86 | 11 | 2 | | EA Perry | Sydney Sixers Women v Hobart Hurricanes Women | Ninja Stadium, Hobart | 2024/25 |
| 50 | 84 | 11 | 1 | | AJ Healy | Sydney Sixers Women v Melbourne Renegades Women | North Sydney Oval, Sydney | 2016/17 |
| 52 | 77 | 10 | 2 | | AJ Healy | Sydney Sixers Women v Hobart Hurricanes Women | Brisbane Cricket Ground, Woolloongabba, Brisbane | 2016/17 |
| 48 | 87* | 12 | 0 | | EA Perry | Sydney Sixers Women v Melbourne Stars Women | Western Australia Cricket Association West Ground, Perth | 2019/20 |
| 50 | 60 | 11 | 1 | | AJ Healy | Sydney Sixers Women v Melbourne Renegades Women | Sydney Showground Stadium, Sydney | 2020/21 |
| 46 | 81 | 10 | 1 | | AJ Healy | Sydney Sixers Women v Melbourne Renegades Women | St Kilda Cricket Ground, Melbourne | 2015/16 |
| 44 | 49 | 11 | 0 | | AJ Healy | Sydney Sixers Women v Sydney Thunder Women | North Sydney Oval, Sydney | 2017/18 |
| 56 | 72 | 5 | 6 | | AK Gardner | Sydney Sixers Women v Adelaide Strikers Women | Adelaide Oval, Adelaide | 2017/18 |
| 46 | 70 | 10 | 1 | | AJ Healy | Sydney Sixers Women v Melbourne Stars Women | St Kilda Cricket Ground, Melbourne | 2018/19 |
| 48 | 70* | 9 | 2 | | AJ Healy | Sydney Sixers Women v Melbourne Renegades Women | Sydney Cricket Ground, Sydney | 2018/19 |
| 46 | 81 | 10 | 1 | | EA Perry | Sydney Sixers Women v Sydney Thunder Women | Drummoyne Oval, Sydney | 2019/20 |
| 44 | 57 | 11 | 0 | | AJ Healy | Sydney Sixers Women v Melbourne Stars Women | Blundstone Arena, Hobart | 2021/22 |
| 54 | 86* | 6 | 5 | | AK Gardner | Sydney Sixers Women v Brisbane Heat Women | Karen Rolton Oval, Adelaide | 2021/22 |
| 48 | 72 | 9 | 2 | | AK Gardner | Sydney Sixers Women v Melbourne Stars Women | North Sydney Oval, Sydney | 2023/24 |
| 44 | 54 | 11 | 0 | | EA Perry | Sydney Sixers Women v Adelaide Strikers Women | North Sydney Oval, Sydney | 2024/25 |
