| Runs |
Wkts |
| 492 | 17 | St Kitts and Nevis Patriots v Guyana Amazon Warriors | Warner Park, Basseterre | 2024 |
| 483 | 10 | St Kitts and Nevis Patriots v Jamaica Tallawahs | Warner Park, Basseterre | 2019 |
| 456 | 12 | St Kitts and Nevis Patriots v Trinbago Knight Riders | Warner Park, Basseterre | 2024 |
| 443 | 6 | Barbados Royals v St Kitts and Nevis Patriots | Kensington Oval, Bridgetown | 2023 |
| 432 | 11 | St Kitts and Nevis Patriots v Trinbago Knight Riders | Warner Park, Basseterre | 2019 |
| 403 | 8 | St Kitts and Nevis Patriots v St Lucia Kings | Warner Park, Basseterre | 2024 |
| 397 | 10 | St Kitts and Nevis Patriots v Barbados Royals | Warner Park, Basseterre | 2023 |
| 390 | 7 | St Kitts and Nevis Patriots v Trinbago Knight Riders | Guyana National Stadium, Providence | 2024 |
| 384 | 13 | Jamaica Tallawahs v St Kitts and Nevis Patriots | Guyana National Stadium, Providence | 2018 |
| 379 | 10 | St Kitts and Nevis Patriots v Jamaica Tallawahs | Warner Park, Basseterre | 2017 |
| 364 | 15 | Trinbago Knight Riders v St Kitts and Nevis Patriots | Queen's Park Oval, Port of Spain | 2018 |
| 359 | 14 | St Lucia Stars v St Kitts and Nevis Patriots | Daren Sammy National Cricket Stadium, Gros Islet | 2017 |
| 359 | 12 | St Kitts and Nevis Patriots v Guyana Amazon Warriors | Warner Park, Basseterre | 2021 |
| 358 | 9 | St Kitts and Nevis Patriots v Trinbago Knight Riders | Warner Park, Basseterre | 2023 |
| 354 | 11 | St Kitts and Nevis Patriots v Barbados Tridents | Warner Park, Basseterre | 2019 |
| 352 | 12 | St Kitts and Nevis Patriots v Trinbago Knight Riders | Warner Park, Basseterre | 2018 |
| 349 | 10 | St Lucia Kings v St Kitts and Nevis Patriots | Daren Sammy National Cricket Stadium, Gros Islet | 2024 |
| 348 | 12 | St Kitts and Nevis Patriots v St Lucia Zouks | Warner Park, Basseterre | 2016 |
| 348 | 11 | St Kitts and Nevis Patriots v St Lucia Kings | Warner Park, Basseterre | 2021 |
| 337 | 13 | St Kitts and Nevis Patriots v Guyana Amazon Warriors | Warner Park, Basseterre | 2018 |
| 337 | 13 | St Kitts and Nevis Patriots v Barbados Tridents | Warner Park, Basseterre | 2018 |
| 335 | 14 | Barbados Tridents v St Kitts and Nevis Patriots | Kensington Oval, Bridgetown | 2016 |
| 335 | 12 | St Kitts and Nevis Patriots v Jamaica Tallawahs | Warner Park, Basseterre | 2021 |
| 334 | 14 | St Kitts and Nevis Patriots v St Lucia Zouks | Brian Lara Stadium, Tarouba | 2020 |
| 334 | 7 | St Kitts and Nevis Patriots v Guyana Amazon Warriors | Warner Park, Basseterre | 2021 |
| 332 | 16 | Jamaica Tallawahs v St Kitts and Nevis Patriots | Sabina Park, Kingston | 2019 |
| 329 | 15 | St Kitts and Nevis Patriots v Guyana Amazon Warriors | Warner Park, Basseterre | 2016 |
| 329 | 12 | St Kitts and Nevis Patriots v Barbados Royals | Warner Park, Basseterre | 2021 |
| 329 | 17 | St Kitts and Nevis Patriots v St Lucia Kings | Brian Lara Stadium, Tarouba | 2022 |
| 329 | 17 | St Kitts and Nevis Patriots v Guyana Amazon Warriors | Warner Park, Basseterre | 2023 |
