| Inns | HS |
| 184-4 | 47 | Southern Vipers v Yorkshire Diamonds | Clifton Park, York | 2019 |
| 172-6 | 55* | Southern Vipers v Loughborough Lightning | Haslegrave Ground, Loughborough | 2018 |
| 172-7 | 73 | Southern Vipers v Western Storm | The 1st Central County Ground, Hove | 2019 |
| 166-7 | 54 | Southern Vipers v Lancashire Thunder | Aigburth, Liverpool | 2019 |
| 163-9 | 34 | Southern Vipers v Yorkshire Diamonds | Clifton Park, York | 2018 |
| 159-7 | 64 | Southern Vipers v Yorkshire Diamonds | The Ageas Bowl, Southampton | 2018 |
| 156-4 | 38 | Southern Vipers v Loughborough Lightning | The Ageas Bowl, Southampton | 2016 |
| 155-9 | 56 | Southern Vipers v Western Storm | County Ground, Bristol | 2019 |
| 153 | 36 | Southern Vipers v Lancashire Thunder | The Ageas Bowl, Southampton | 2018 |
| 147-9 | 82 | Southern Vipers v Surrey Stars | The 1st Central County Ground, Hove | 2018 |
| 145-5 | 31 | Southern Vipers v Western Storm | The 1st Central County Ground, Hove | 2017 |
| 145-3 | 62* | Southern Vipers v Surrey Stars | Woodbridge Road, Guildford | 2018 |
| 145-5 | 37 | Southern Vipers v Loughborough Lightning | The 1st Central County Ground, Hove | 2019 |
| 143-3 | 52 | Southern Vipers v Western Storm | The Essex County Ground, Chelmsford | 2016 |
| 142-5 | 44* | Southern Vipers v Western Storm | The Ageas Bowl, Southampton | 2019 |
| 138-6 | 50* | Southern Vipers v Yorkshire Diamonds | Arundel Castle Cricket Club Ground, Arundel | 2017 |
| 137-3 | 57 | Southern Vipers v Western Storm | The Cooper Associates County Ground, Taunton | 2016 |
| 136-8 | 40 | Southern Vipers v Loughborough Lightning | Haslegrave Ground, Loughborough | 2019 |
| 133-9 | 40 | Southern Vipers v Lancashire Thunder | Aigburth, Liverpool | 2018 |
| 132-4 | 54* | Southern Vipers v Lancashire Thunder | Stanley Park, Blackpool | 2016 |
| 132-8 | 51 | Southern Vipers v Lancashire Thunder | The 1st Central County Ground, Hove | 2019 |
| 127-9 | 59 | Southern Vipers v Yorkshire Diamonds | The Ageas Bowl, Southampton | 2019 |
| 127 | 36 | Southern Vipers v Loughborough Lightning | The Ageas Bowl, Southampton | 2019 |
| 118-4 | 45* | Southern Vipers v Yorkshire Diamonds | The Ageas Bowl (Nursery), Southampton | 2016 |
| 105 | 37 | Southern Vipers v Loughborough Lightning | The Ageas Bowl, Southampton | 2018 |
| 100-7 | 50* | Southern Vipers v Surrey Stars | The Ageas Bowl, Southampton | 2017 |
| 91 | 31 | Southern Vipers v Western Storm | Arundel Castle Cricket Club Ground, Arundel | 2018 |
| 88-4 | 41 | Southern Vipers v Surrey Stars | The Ageas Bowl, Southampton | 2016 |
| 88-4 | 46* | Southern Vipers v Lancashire Thunder | Aigburth, Liverpool | 2017 |
| 73-1 | 47* | Southern Vipers v Western Storm | The Ageas Bowl, Southampton | 2017 |
