| Balls |
| 485 | DJ McGlew | South Africa v Australia | Kingsmead, Durban | 1957/58 |
| 380 | JHB Waite | South Africa v Australia | Kingsmead, Durban | 1957/58 |
| 376 | CN Frank | South Africa v Australia | Old Wanderers, Johannesburg | 1921/22 |
| 346 | B Mitchell | South Africa v England | Newlands, Cape Town | 1930/31 |
| 336 | WJ Cronje | South Africa v India | St George's Park, Port Elizabeth | 1992/93 |
| 335 | AD Nourse | South Africa v England | Kingsmead, Durban | 1938/39 |
| 325 | G Kirsten | South Africa v England | Old Trafford, Manchester | 1998 |
| 325 | AJ Hall | South Africa v India | Modi Stadium, Kanpur | 2004/05 |
| 316 | PGV van der Bijl | South Africa v England | Kingsmead, Durban | 1938/39 |
| 316 | AJ Pithey | South Africa v England | Newlands, Cape Town | 1964/65 |
| 316 | JH Kallis | South Africa v West Indies | Bourda, Georgetown | 2004/05 |
| 313 | B Mitchell | South Africa v England | Newlands, Cape Town | 1948/49 |
| 310 | F du Plessis | South Africa v Australia | Adelaide Oval, Adelaide | 2012/13 |
| 308 | ND McKenzie | South Africa v England | Lord's Cricket Ground, St John's Wood | 2008 |
| 305 | AD Nourse | South Africa v England | Trent Bridge, Nottingham | 1951 |
| 292 | B Mitchell | South Africa v England | Kennington Oval, Kennington | 1947 |
| 286 | HW Taylor | South Africa v England | Kingsmead, Durban | 1922/23 |
| 286 | JA Rudolph | South Africa v Sri Lanka | Galle International Stadium, Galle | 2004 |
| 284 | B Mitchell | South Africa v England | Kennington Oval, Kennington | 1947 |
| 280 | KC Bland | South Africa v Australia | Sydney Cricket Ground, Sydney | 1963/64 |
| 280 | G Kirsten | South Africa v England | Kingsmead, Durban | 1999/00 |
| 280 | JH Kallis | South Africa v Zimbabwe | Queens Sports Club, Bulawayo | 2001/02 |
| 279 | JHB Waite | South Africa v Australia | New Wanderers Stadium, Johannesburg | 1957/58 |
| 277 | JH Kallis | South Africa v West Indies | Newlands, Cape Town | 1998/99 |
| 276 | EJ Barlow | South Africa v Australia | Newlands, Cape Town | 1969/70 |
| 273 | EAB Rowan | South Africa v England | Ellis Park, Johannesburg | 1948/49 |
| 273 | JH Kallis | South Africa v India | Sahara Stadium Kingsmead, Durban | 2013/14 |
| 270 | JHB Waite | South Africa v England | Old Trafford, Manchester | 1955 |
| 269 | EJ Barlow | South Africa v England | Newlands, Cape Town | 1964/65 |
| 268 | HH Gibbs | South Africa v New Zealand | Jade Stadium, Christchurch | 1998/99 |
| 268 | JA Rudolph | South Africa v Australia | Western Australia Cricket Association Ground, Perth | 2005/06 |
| 268 | HM Amla | South Africa v India | Eden Gardens, Kolkata | 2009/10 |
