| Runs |
Wkts |
| 517 | 9 | South Africa v West Indies | SuperSport Park, Centurion | 2022/23 |
| 467 | 13 | South Africa v West Indies | Bidvest Wanderers Stadium, Johannesburg | 2014/15 |
| 459 | 12 | England v South Africa | Wankhede Stadium, Mumbai | 2015/16 |
| 458 | 6 | India v South Africa | Nehru Stadium, Guwahati | 2022/23 |
| 448 | 11 | South Africa v England | SuperSport Park, Centurion | 2019/20 |
| 433 | 14 | South Africa v West Indies | Imperial Wanderers Stadium, Johannesburg | 2022/23 |
| 431 | 11 | South Africa v India | Imperial Wanderers Stadium, Johannesburg | 2024/25 |
| 427 | 14 | England v South Africa | Seat Unique Stadium, Bristol | 2022 |
| 427 | 13 | South Africa v India | SuperSport Park, Centurion | 2024/25 |
| 423 | 7 | India v South Africa | Feroz Shah Kotla, Delhi | 2022 |
| 416 | 8 | South Africa v Pakistan | SuperSport Park, Centurion | 2024/25 |
| 413 | 8 | South Africa v West Indies | Liberty Life Wanderers Stadium, Johannesburg | 2007/08 |
| 409 | 12 | South Africa v Australia | Bidvest Wanderers Stadium, Johannesburg | 2015/16 |
| 408 | 6 | South Africa v Pakistan | SuperSport Park, Centurion | 2020/21 |
| 406 | 14 | South Africa v England | Hollywoodbets Kingsmead, Durban | 2019/20 |
| 405 | 13 | India v South Africa | Holkar Stadium, Indore | 2022/23 |
| 401 | 14 | Ireland v South Africa | Seat Unique Stadium, Bristol | 2022 |
| 400 | 11 | South Africa v Australia | Liberty Life Wanderers Stadium, Johannesburg | 2005/06 |
| 399 | 8 | India v South Africa | Himachal Pradesh Cricket Association Stadium, Dharamsala | 2015/16 |
| 398 | 14 | South Africa v England | SuperSport Park, Centurion | 2009/10 |
| 398 | 14 | West Indies v South Africa | Sabina Park, Kingston | 2023/24 |
| 389 | 12 | England v South Africa | Zohur Ahmed Chowdhury Stadium, Chittagong | 2013/14 |
| 383 | 4 | South Africa v England | PPC Newlands, Cape Town | 2020/21 |
| 383 | 17 | Australia v South Africa | Marrara Cricket Ground, Darwin | 2025 |
| 381 | 15 | Afghanistan v South Africa | Wankhede Stadium, Mumbai | 2015/16 |
| 381 | 13 | South Africa v Australia | Hollywoodbets Kingsmead, Durban | 2023/24 |
| 380 | 13 | South Africa v Zimbabwe | De Beers Diamond Oval, Kimberley | 2010/11 |
| 380 | 15 | Ireland v South Africa | Sheikh Zayed Stadium, Abu Dhabi | 2024 |
| 378 | 14 | South Africa v India | Bidvest Wanderers Stadium, Johannesburg | 2017/18 |
| 378 | 15 | South Africa v Pakistan | PPC Newlands, Cape Town | 2018/19 |
