| Runs |
Out of |
4s |
6s |
| 96 | 125* | 12 | 8 | | DT Brevis | South Africa v Australia | Marrara Cricket Ground, Darwin | 2025 |
| 98 | 117* | 5 | 13 | | RE Levi | South Africa v New Zealand | Seddon Park, Hamilton | 2011/12 |
| 84 | 100 | 9 | 8 | | Q de Kock | South Africa v West Indies | SuperSport Park, Centurion | 2022/23 |
| 88 | 117 | 7 | 10 | | RR Hendricks | South Africa v Pakistan | SuperSport Park, Centurion | 2024/25 |
| 68 | 90* | 14 | 2 | | HH Gibbs | South Africa v West Indies | Liberty Life Wanderers Stadium, Johannesburg | 2007/08 |
| 74 | 119 | 11 | 5 | | F du Plessis | South Africa v West Indies | Bidvest Wanderers Stadium, Johannesburg | 2014/15 |
| 78 | 114* | 9 | 7 | | MN van Wyk | South Africa v West Indies | Sahara Stadium Kingsmead, Durban | 2014/15 |
| 82 | 101* | 7 | 9 | | DA Miller | South Africa v Bangladesh | Senwes Park, Potchefstroom | 2017/18 |
| 70 | 96* | 10 | 5 | | RR Rossouw | South Africa v England | Sophia Gardens, Cardiff | 2022 |
| 74 | 106* | 8 | 7 | | DA Miller | South Africa v India | Nehru Stadium, Guwahati | 2022/23 |
| 76 | 100* | 7 | 8 | | RR Rossouw | South Africa v India | Holkar Stadium, Indore | 2022/23 |
| 76 | 109 | 7 | 8 | | RR Rossouw | South Africa v Bangladesh | Sydney Cricket Ground, Sydney | 2022/23 |
| 74 | 94 | 5 | 9 | | LE Bosman | South Africa v England | SuperSport Park, Centurion | 2009/10 |
| 68 | 88 | 8 | 6 | | GC Smith | South Africa v England | SuperSport Park, Centurion | 2009/10 |
| 64 | 96* | 10 | 4 | | JP Duminy | South Africa v Zimbabwe | De Beers Diamond Oval, Kimberley | 2010/11 |
| 60 | 71* | 9 | 4 | | GC Smith | South Africa v Pakistan | Liberty Life Wanderers Stadium, Johannesburg | 2006/07 |
| 58 | 85 | 10 | 3 | | F du Plessis | South Africa v Sri Lanka | Mahinda Rajapaksha International Cricket Stadium, Hambantota | 2013 |
| 58 | 86* | 10 | 3 | | JP Duminy | South Africa v New Zealand | Zohur Ahmed Chowdhury Stadium, Chittagong | 2013/14 |
| 56 | 68 | 11 | 2 | | RR Hendricks | South Africa v West Indies | SuperSport Park, Centurion | 2022/23 |
| 56 | 83 | 11 | 2 | | RR Hendricks | South Africa v West Indies | Imperial Wanderers Stadium, Johannesburg | 2022/23 |
| 50 | 89* | 11 | 1 | | GC Smith | South Africa v Australia | Liberty Life Wanderers Stadium, Johannesburg | 2005/06 |
| 60 | 89* | 6 | 6 | | JM Kemp | South Africa v New Zealand | Sahara Stadium Kingsmead, Durban | 2007/08 |
| 54 | 69* | 9 | 3 | | AB de Villiers | South Africa v England | Zohur Ahmed Chowdhury Stadium, Chittagong | 2013/14 |
| 60 | 71 | 6 | 6 | | AB de Villiers | South Africa v England | Bidvest Wanderers Stadium, Johannesburg | 2015/16 |
| 56 | 97* | 8 | 4 | | HM Amla | South Africa v Australia | PPC Newlands, Cape Town | 2015/16 |
| 50 | 85 | 11 | 1 | | HM Amla | South Africa v Bangladesh | Senwes Park, Potchefstroom | 2017/18 |
| 62 | 85* | 5 | 7 | | DA Miller | South Africa v Pakistan | Gaddafi Stadium, Lahore | 2020/21 |
| 58 | 75* | 7 | 5 | | HE van der Dussen | South Africa v India | Feroz Shah Kotla, Delhi | 2022 |
| 58 | 81 | 7 | 5 | | H Klaasen | South Africa v India | Barabati Stadium, Cuttack | 2022 |
| 60 | 87 | 6 | 6 | | RR Hendricks | South Africa v West Indies | Sabina Park, Kingston | 2023/24 |
| 58 | 74 | 7 | 5 | | Q de Kock | South Africa v United States of America | Sir Vivian Richards Stadium, North Sound | 2024 |
| 64 | 82 | 4 | 8 | | DA Miller | South Africa v Pakistan | Hollywoodbets Kingsmead, Durban | 2024/25 |
