Most Runs in a Match against Eastern Province
| 316 | G Kirsten | for Western Province | Newlands, Cape Town | 2001/02 | f46418 |
| 302 | AJ Lamb | for Orange Free State | University of Orange Free State Ground, Bloemfontein | 1987/88 | f37270 |
| 300 | M Marais | for Border | Buffalo Park, East London | 2017/18 | f58286 |
| 286 | JP Crawley | for England A | St George's Park, Port Elizabeth | 1993/94 | f40825 |
| 276 | PN Kirsten | for Western Province | Newlands, Cape Town | 1976/77 | f31327 |
| 258 | JD Nel | for Western Province | St George's Park, Port Elizabeth | 1952/53 | f19857 |
| 254 | TG Mokoena | for Easterns | Sahara Park Willowmoore, Benoni | 2015/16 | f56572 |
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