| Runs |
Out of |
4s |
6s |
| 70 | 116 | 13 | 3 | | HH Gibbs | South Africa v Kenya | R Premadasa Stadium, Colombo | 2002/03 |
| 64 | 116* | 16 | 0 | | HH Gibbs | South Africa v India | R Premadasa Stadium, Colombo | 2002/03 |
| 64 | 141 | 16 | 0 | | GC Smith | South Africa v England | SuperSport Park, Centurion | 2009/10 |
| 64 | 100* | 10 | 4 | | DA Miller | South Africa v New Zealand | Gaddafi Stadium, Lahore | 2024/25 |
| 52 | 69 | 13 | 0 | | DJ Cullinan | South Africa v England | Bangabandhu National Stadium, Dhaka | 1998/99 |
| 50 | 71* | 11 | 1 | | R McLaren | South Africa v India | The SWALEC Stadium, Cardiff | 2013 |
| 48 | 65* | 9 | 2 | | HH Dippenaar | South Africa v England | Gymkhana Club Ground, Nairobi | 2000/01 |
| 44 | 64 | 11 | 0 | | H Klaasen | South Africa v England | National Bank Cricket Arena, Karachi | 2024/25 |
| 50 | 113* | 5 | 5 | | JH Kallis | South Africa v Sri Lanka | Bangabandhu National Stadium, Dhaka | 1998/99 |
| 40 | 78* | 10 | 0 | | JH Kallis | South Africa v England | Gymkhana Club Ground, Nairobi | 2000/01 |
| 42 | 101 | 9 | 1 | | HH Gibbs | South Africa v West Indies | The Brit Oval, Kennington | 2004 |
| 42 | 58 | 9 | 1 | | GC Smith | South Africa v Sri Lanka | SuperSport Park, Centurion | 2009/10 |
| 36 | 60 | 9 | 0 | | MV Boucher | South Africa v India | Gymkhana Club Ground, Nairobi | 2000/01 |
| 36 | 40* | 9 | 0 | | JH Kallis | South Africa v Bangladesh | Edgbaston, Birmingham | 2004 |
| 36 | 70* | 9 | 0 | | AB de Villiers | South Africa v New Zealand | SuperSport Park, Centurion | 2009/10 |
| 36 | 81 | 9 | 0 | | HM Amla | South Africa v Pakistan | Edgbaston, Birmingham | 2013 |
| 42 | 72* | 6 | 3 | | HE van der Dussen | South Africa v England | National Bank Cricket Arena, Karachi | 2024/25 |
| 32 | 61 | 8 | 0 | | JN Rhodes | South Africa v West Indies | Sinhalese Sports Club Ground, Colombo | 2002/03 |
| 36 | 73 | 6 | 2 | | CA Ingram | South Africa v West Indies | The SWALEC Stadium, Cardiff | 2013 |
| 34 | 103 | 7 | 1 | | RD Rickelton | South Africa v Afghanistan | National Bank Cricket Arena, Karachi | 2024/25 |
| 32 | 67 | 5 | 2 | | WJ Cronje | South Africa v England | Bangabandhu National Stadium, Dhaka | 1998/99 |
| 28 | 32 | 7 | 0 | | G Kirsten | South Africa v England | Gymkhana Club Ground, Nairobi | 2000/01 |
| 30 | 97 | 6 | 1 | | JH Kallis | South Africa v India | R Premadasa Stadium, Colombo | 2002/03 |
| 28 | 69 | 7 | 0 | | MV Boucher | South Africa v Pakistan | Punjab Cricket Association Stadium, Mohali | 2006/07 |
| 28 | 70 | 7 | 0 | | AB de Villiers | South Africa v India | The SWALEC Stadium, Cardiff | 2013 |
| 32 | 56* | 5 | 2 | | DA Miller | South Africa v England | The Kia Oval, Kennington | 2013 |
| 32 | 103 | 5 | 2 | | HM Amla | South Africa v Sri Lanka | The Kia Oval, Kennington | 2017 |
| 30 | 52* | 6 | 1 | | AK Markram | South Africa v Afghanistan | National Bank Cricket Arena, Karachi | 2024/25 |
| 24 | 41 | 6 | 0 | | MJR Rindel | South Africa v England | Bangabandhu National Stadium, Dhaka | 1998/99 |
| 24 | 49 | 6 | 0 | | MJR Rindel | South Africa v West Indies | Bangabandhu National Stadium, Dhaka | 1998/99 |
| 26 | 60 | 5 | 1 | | JH Kallis | South Africa v Kenya | R Premadasa Stadium, Colombo | 2002/03 |
| 24 | 69 | 6 | 0 | | GC Smith | South Africa v Kenya | R Premadasa Stadium, Colombo | 2002/03 |
| 24 | 42* | 6 | 0 | | GC Smith | South Africa v Bangladesh | Edgbaston, Birmingham | 2004 |
| 28 | 64 | 4 | 2 | | JM Kemp | South Africa v Pakistan | Punjab Cricket Association Stadium, Mohali | 2006/07 |
| 24 | 39 | 6 | 0 | | LE Bosman | South Africa v West Indies | Sawai Mansingh Stadium, Jaipur | 2006/07 |
| 24 | 36 | 6 | 0 | | JH Kallis | South Africa v New Zealand | SuperSport Park, Centurion | 2009/10 |
| 24 | 68 | 6 | 0 | | RJ Peterson | South Africa v India | The SWALEC Stadium, Cardiff | 2013 |
| 26 | 38* | 5 | 1 | | JP Duminy | South Africa v Sri Lanka | The Kia Oval, Kennington | 2017 |
| 24 | 75 | 6 | 0 | | F du Plessis | South Africa v Sri Lanka | The Kia Oval, Kennington | 2017 |
| 28 | 69 | 4 | 2 | | HE van der Dussen | South Africa v New Zealand | Gaddafi Stadium, Lahore | 2024/25 |
