| Runs |
Wkts |
| 445 | 12 | Melbourne Renegades v Hobart Hurricanes | Etihad Stadium, Melbourne | 2016/17 |
| 414 | 10 | Perth Scorchers v Melbourne Renegades | Optus Stadium, Perth | 2022/23 |
| 397 | 15 | Brisbane Heat v Melbourne Renegades | Brisbane Cricket Ground, Woolloongabba, Brisbane | 2016/17 |
| 395 | 11 | Melbourne Renegades v Brisbane Heat | Marvel Stadium, Melbourne | 2024/25 |
| 391 | 10 | Melbourne Renegades v Perth Scorchers | Marvel Stadium, Melbourne | 2021/22 |
| 384 | 10 | Adelaide Strikers v Melbourne Renegades | Adelaide Oval, Adelaide | 2022/23 |
| 381 | 13 | Perth Scorchers v Melbourne Renegades | Optus Stadium, Perth | 2019/20 |
| 380 | 5 | Melbourne Renegades v Perth Scorchers | Etihad Stadium, Melbourne | 2011/12 |
| 376 | 7 | Melbourne Renegades v Hobart Hurricanes | Marvel Stadium, Melbourne | 2019/20 |
| 371 | 8 | Perth Scorchers v Melbourne Renegades | Western Australia Cricket Association Ground, Perth | 2017/18 |
| 370 | 9 | Hobart Hurricanes v Melbourne Renegades | Blundstone Arena, Hobart | 2023/24 |
| 369 | 16 | Sydney Thunder v Melbourne Renegades | Manuka Oval, Canberra | 2017/18 |
| 364 | 8 | Brisbane Heat v Melbourne Renegades | Brisbane Cricket Ground, Woolloongabba, Brisbane | 2015/16 |
| 364 | 10 | Melbourne Renegades v Sydney Sixers | Marvel Stadium, Melbourne | 2018/19 |
| 363 | 13 | Melbourne Renegades v Brisbane Heat | Etihad Stadium, Melbourne | 2013/14 |
| 358 | 11 | Melbourne Renegades v Hobart Hurricanes | Marvel Stadium, Melbourne | 2021/22 |
| 355 | 9 | Adelaide Strikers v Melbourne Renegades | Adelaide Oval, Adelaide | 2017/18 |
| 355 | 11 | Adelaide Strikers v Melbourne Renegades | Adelaide Oval, Adelaide | 2020/21 |
| 355 | 12 | Melbourne Renegades v Adelaide Strikers | Marvel Stadium, Melbourne | 2023/24 |
| 354 | 16 | Melbourne Renegades v Melbourne Stars | Etihad Stadium, Melbourne | 2016/17 |
| 353 | 9 | Melbourne Renegades v Perth Scorchers | GMHBA Stadium, Geelong | 2019/20 |
| 351 | 12 | Melbourne Renegades v Brisbane Heat | Etihad Stadium, Melbourne | 2012/13 |
| 351 | 8 | Sydney Sixers v Melbourne Renegades | Sydney Cricket Ground, Sydney | 2019/20 |
| 350 | 10 | Adelaide Strikers v Melbourne Renegades | Adelaide Oval, Adelaide | 2018/19 |
| 350 | 14 | Hobart Hurricanes v Melbourne Renegades | Blundstone Arena, Hobart | 2018/19 |
| 349 | 12 | Perth Scorchers v Melbourne Renegades | Western Australia Cricket Association Ground, Perth | 2014/15 |
| 349 | 10 | Sydney Thunder v Melbourne Renegades | Spotless Stadium, Sydney | 2015/16 |
| 349 | 12 | Melbourne Renegades v Sydney Thunder | Marvel Stadium, Melbourne | 2022/23 |
| 348 | 13 | Brisbane Heat v Melbourne Renegades | Brisbane Cricket Ground, Woolloongabba, Brisbane | 2017/18 |
| 347 | 7 | Hobart Hurricanes v Melbourne Renegades | Bellerive Oval, Hobart | 2011/12 |
