| Wkt |
| 1 | 177 | LWP Wells (87) & KK Jennings (95) | Lancashire v Nottinghamshire | Emirates Old Trafford, Manchester | 2025 |
| 1 | 170 | AL Davies (65) & KK Jennings (108) | Lancashire v Durham | Emirates Riverside, Chester-le-Street | 2020 |
| 2 | 162* | VVS Laxman (78*) & SJ Croft (83*) | Lancashire v Nottinghamshire | Trent Bridge, Nottingham | 2009 |
| 2 | 160 | MB Loye (100) & BJ Hodge (68) | Lancashire v Durham | Old Trafford, Manchester | 2005 |
| 1 | 160 | AL Davies (50*) & LS Livingstone (100) | Lancashire v Derbyshire | The 3aaa County Ground, Derby | 2018 |
| 2 | 154 | SG Law (67) & BJ Hodge (90*) | Lancashire v Derbyshire | County Ground, Derby | 2005 |
| 4 | 151* | SJ Croft (94*) & JP Faulkner (47*) | Lancashire v Derbyshire | Emirates Old Trafford, Manchester | 2015 |
| 4 | 146 | SJ Croft (101) & DJ Mitchell (48) | Lancashire v Northamptonshire | County Ground, Northampton | 2023 |
| 4 | 131* | KR Brown (67*) & SJ Croft (76*) | Lancashire v Derbyshire | The 3aaa County Ground, Derby | 2014 |
| 2 | 130 | LS Livingstone (69) & SJ Croft (58) | Lancashire v Yorkshire | Emirates Old Trafford, Manchester | 2020 |
| 3 | 128 | TC Smith (74) & PJ Horton (71*) | Lancashire v Worcestershire | Emirates Old Trafford, Manchester | 2014 |
| 2 | 123 | PD Salt (80) & JC Buttler (54) | Lancashire v Northamptonshire | County Ground, Northampton | 2025 |
| 1 | 119 | SC Moore (80) & TC Smith (56) | Lancashire v Nottinghamshire | Trent Bridge, Nottingham | 2012 |
| 1 | 118 | KK Jennings (88) & FH Allen (60) | Lancashire v Nottinghamshire | Emirates Old Trafford, Manchester | 2021 |
| 3 | 114 | SJ Croft (61*) & DJ Vilas (55) | Lancashire v Nottinghamshire | Stanley Park, Blackpool | 2022 |
| 4 | 113 | MB Loye (80*) & SJ Croft (49) | Lancashire v Durham | Old Trafford, Manchester | 2007 |
| 1 | 112* | MB Loye (54*) & L Vincent (50*) | Lancashire v Derbyshire | County Ground, Derby | 2008 |
| 1 | 112 | FH Allen (66) & KK Jennings (54*) | Lancashire v Northamptonshire | Emirates Old Trafford, Manchester | 2021 |
| 3 | 112 | KK Jennings (75) & DJ Vilas (63*) | Lancashire v Yorkshire | Edgbaston, Birmingham | 2022 |
| 2 | 112 | PD Salt (70) & LS Livingstone (54*) | Lancashire v Nottinghamshire | Emirates Old Trafford, Manchester | 2024 |
| 1 | 110* | SC Moore (52*) & TC Smith (58*) | Lancashire v Warwickshire | Edgbaston, Birmingham | 2011 |
| 5 | 107 | GJ Maxwell (73) & DJ Vilas (46) | Lancashire v Nottinghamshire | Emirates Old Trafford, Manchester | 2019 |
| 4 | 107 | KK Jennings (35) & GJ Maxwell (79) | Lancashire v Warwickshire | Edgbaston, Birmingham | 2019 |
| 1 | 106 | MB Loye (47) & SG Law (101) | Lancashire v Yorkshire | Old Trafford, Manchester | 2005 |
| 4 | 104* | F du Plessis (78*) & AG Prince (29*) | Lancashire v Leicestershire | Grace Road, Leicester | 2009 |
| 2 | 103 | TC Smith (40) & SJ Croft (65*) | Lancashire v Durham | Old Trafford, Manchester | 2012 |
| 1 | 102 | LWP Wells (83) & KK Jennings (33) | Lancashire v Derbyshire | The Central Co-op County Ground, Derby | 2025 |
| 1 | 101 | FH Allen (66) & KK Jennings (43) | Lancashire v Durham | Emirates Old Trafford, Manchester | 2021 |
| 2 | 101 | JC Buttler (83) & LS Livingstone (47*) | Lancashire v Derbyshire | Emirates Old Trafford, Manchester | 2023 |
| 1 | 100 | MB Loye (27) & L Vincent (102*) | Lancashire v Derbyshire | Old Trafford, Manchester | 2008 |
