| Runs |
Out of |
4s |
6s |
| 96 | 117 | 12 | 8 | | Sharjeel Khan | Islamabad United v Peshawar Zalmi | Dubai Sports City Stadium, Dubai | 2015/16 |
| 88 | 117* | 13 | 6 | | CS Delport | Islamabad United v Lahore Qalandars | National Stadium, Karachi | 2018/19 |
| 82 | 106 | 13 | 5 | | Sahibzada Farhan | Islamabad United v Peshawar Zalmi | Rawalpindi Cricket Stadium, Rawalpindi | 2024/25 |
| 78 | 94* | 12 | 5 | | L Ronchi | Islamabad United v Karachi Kings | Dubai Sports City Stadium, Dubai | 2017/18 |
| 78 | 90* | 12 | 5 | | C Munro | Islamabad United v Quetta Gladiators | Sheikh Zayed Stadium, Abu Dhabi | 2021 |
| 84 | 97 | 9 | 8 | | Azam Khan | Islamabad United v Quetta Gladiators | National Bank Cricket Arena, Karachi | 2022/23 |
| 70 | 105* | 13 | 3 | | Usman Khawaja | Islamabad United v Peshawar Zalmi | Sheikh Zayed Stadium, Abu Dhabi | 2021 |
| 60 | 88* | 12 | 2 | | C Munro | Islamabad United v Karachi Kings | Sheikh Zayed Stadium, Abu Dhabi | 2021 |
| 58 | 82* | 13 | 1 | | AD Hales | Islamabad United v Peshawar Zalmi | National Stadium, Karachi | 2021/22 |
| 74 | 91 | 5 | 9 | | Shadab Khan | Islamabad United v Multan Sultans | National Stadium, Karachi | 2021/22 |
| 66 | 84 | 9 | 5 | | C Munro | Islamabad United v Multan Sultans | Rawalpindi Cricket Stadium, Rawalpindi | 2023/24 |
| 72 | 88 | 6 | 8 | | AD Hales | Islamabad United v Karachi Kings | Rawalpindi Cricket Stadium, Rawalpindi | 2024/25 |
| 58 | 71 | 10 | 3 | | L Ronchi | Islamabad United v Karachi Kings | Sharjah Cricket Association Stadium, Sharjah | 2017/18 |
| 66 | 85 | 6 | 7 | | Azam Khan | Islamabad United v Peshawar Zalmi | Gaddafi Stadium, Lahore | 2021/22 |
| 62 | 79* | 5 | 7 | | Sharjeel Khan | Islamabad United v Lahore Qalandars | Sharjah Cricket Association Stadium, Sharjah | 2015/16 |
| 56 | 72* | 8 | 4 | | Azam Khan | Islamabad United v Karachi Kings | Rawalpindi Cricket Stadium, Rawalpindi | 2022/23 |
| 60 | 75 | 6 | 6 | | Azam Khan | Islamabad United v Peshawar Zalmi | Gaddafi Stadium, Lahore | 2023/24 |
| 56 | 82 | 8 | 4 | | C Munro | Islamabad United v Karachi Kings | National Bank Cricket Arena, Karachi | 2023/24 |
| 54 | 73 | 9 | 3 | | Sahibzada Farhan | Islamabad United v Karachi Kings | Rawalpindi Cricket Stadium, Rawalpindi | 2024/25 |
| 58 | 79 | 4 | 7 | | SR Watson | Islamabad United v Lahore Qalandars | Sharjah Cricket Association Stadium, Sharjah | 2015/16 |
| 52 | 73 | 7 | 4 | | DR Smith | Islamabad United v Quetta Gladiators | Dubai Sports City Stadium, Dubai | 2015/16 |
| 50 | 73 | 8 | 3 | | BJ Haddin | Islamabad United v Peshawar Zalmi | Dubai Sports City Stadium, Dubai | 2016/17 |
| 50 | 78* | 8 | 3 | | SW Billings | Islamabad United v Quetta Gladiators | Sharjah Cricket Association Stadium, Sharjah | 2016/17 |
| 56 | 77 | 5 | 6 | | L Ronchi | Islamabad United v Lahore Qalandars | Dubai Sports City Stadium, Dubai | 2017/18 |
| 50 | 67* | 8 | 3 | | L Ronchi | Islamabad United v Karachi Kings | Sharjah Cricket Association Stadium, Sharjah | 2018/19 |
| 56 | 70 | 5 | 6 | | Asif Ali | Islamabad United v Karachi Kings | Dubai Sports City Stadium, Dubai | 2018/19 |
| 48 | 74 | 9 | 2 | | L Ronchi | Islamabad United v Multan Sultans | Gaddafi Stadium, Lahore | 2019/20 |
| 48 | 85* | 9 | 2 | | L Ronchi | Islamabad United v Karachi Kings | Rawalpindi Cricket Stadium, Rawalpindi | 2019/20 |
| 50 | 87* | 8 | 3 | | C Munro | Islamabad United v Lahore Qalandars | Gaddafi Stadium, Lahore | 2019/20 |
| 54 | 75 | 6 | 5 | | Asif Ali | Islamabad United v Lahore Qalandars | Sheikh Zayed Stadium, Abu Dhabi | 2021 |
| 52 | 62 | 7 | 4 | | Rahmanullah Gurbaz | Islamabad United v Peshawar Zalmi | National Bank Cricket Arena, Karachi | 2022/23 |
| 54 | 74* | 6 | 5 | | Shadab Khan | Islamabad United v Lahore Qalandars | Gaddafi Stadium, Lahore | 2023/24 |
| 54 | 80* | 6 | 5 | | AGS Gous | Islamabad United v Multan Sultans | Multan Cricket Stadium, Multan | 2024/25 |
