| 245 | BKG Mendis | Sri Lanka v Ireland | Galle International Stadium, Galle | 2022/23 |
| 205 | KNM Fernando | Sri Lanka v Ireland | Galle International Stadium, Galle | 2022/23 |
| 205 | OJD Pope | England v Ireland | Lord's Cricket Ground, St John's Wood | 2023 |
| 182 | BM Duckett | England v Ireland | Lord's Cricket Ground, St John's Wood | 2023 |
| 179 | FDM Karunaratne | Sri Lanka v Ireland | Galle International Stadium, Galle | 2022/23 |
| 177 | Mushfiqur Rahim | Bangladesh v Ireland | Shere Bangla National Stadium, Mirpur | 2022/23 |
| 174 | Rahmat Shah | Afghanistan v Ireland | Rajiv Gandhi International Cricket Stadium, Dehra Dun | 2018/19 |
| 171 | Mahmudul Hasan | Bangladesh v Ireland | Sylhet Stadium, Sylhet | 2025/26 |
| 159 | Mushfiqur Rahim | Bangladesh v Ireland | Shere Bangla National Stadium, Mirpur | 2025/26 |
| 150 | Mominul Haque | Bangladesh v Ireland | Shere Bangla National Stadium, Mirpur | 2025/26 |
| 140 | BKG Mendis | Sri Lanka v Ireland | Galle International Stadium, Galle | 2022/23 |
| 128 | Liton Das | Bangladesh v Ireland | Shere Bangla National Stadium, Mirpur | 2025/26 |
| 115 | FDM Karunaratne | Sri Lanka v Ireland | Galle International Stadium, Galle | 2022/23 |
| 113 | Shadman Islam | Bangladesh v Ireland | Shere Bangla National Stadium, Mirpur | 2025/26 |
| 110 | WN Madhevere | Zimbabwe v Ireland | Queens Sports Club, Bulawayo | 2024/25 |
| 104 | WSR Samarawickrama | Sri Lanka v Ireland | Galle International Stadium, Galle | 2022/23 |
| 102 | LD Chandimal | Sri Lanka v Ireland | Galle International Stadium, Galle | 2022/23 |
| 100 | AD Mathews | Sri Lanka v Ireland | Galle International Stadium, Galle | 2022/23 |
| 100 | Nazmul Hossain | Bangladesh v Ireland | Sylhet Stadium, Sylhet | 2025/26 |
| 95 | NR Welch | Zimbabwe v Ireland | Queens Sports Club, Bulawayo | 2024/25 |
| 94 | Mahmudul Hasan | Bangladesh v Ireland | Shere Bangla National Stadium, Mirpur | 2025/26 |
| 93 | MJ Leach | England v Ireland | Lord's Cricket Ground, St John's Wood | 2019 |
| 87 | Shakib Al Hasan | Bangladesh v Ireland | Shere Bangla National Stadium, Mirpur | 2022/23 |
| 86 | PS Masvaure | Zimbabwe v Ireland | Civil Service Cricket Club, Stormont, Belfast | 2024 |
| 83 | Fahim Ashraf | Pakistan v Ireland | The Village, Malahide, Dublin | 2018 |
| 82 | Mominul Haque | Bangladesh v Ireland | Sylhet Stadium, Sylhet | 2025/26 |
| 81 | Imam-ul-Haq | Pakistan v Ireland | The Village, Malahide, Dublin | 2018 |
| 80 | Shadman Islam | Bangladesh v Ireland | Sylhet Stadium, Sylhet | 2025/26 |
| 77 | JJ Roy | England v Ireland | Lord's Cricket Ground, St John's Wood | 2019 |
| 75 | Hashmatullah Shahidi | Afghanistan v Ireland | Tolerance Oval, Abu Dhabi | 2023/24 |
| 75 | SC Williams | Zimbabwe v Ireland | Civil Service Cricket Club, Stormont, Belfast | 2024 |
