| Runs |
Wkts |
| 390 | 9 | East Lancashire v Enfield | Alexandra Meadows, Blackburn | 2022 |
| 353 | 9 | Enfield v East Lancashire | Dill Hall Lane, Enfield | 2013 |
| 346 | 8 | Rishton v East Lancashire | Blackburn Road, Rishton | 2009 |
| 331 | 6 | Burnley v East Lancashire | The boohoo.com Turf Moor, Burnley | 2023 |
| 326 | 12 | East Lancashire v Lowerhouse | Alexandra Meadows, Blackburn | 2023 |
| 325 | 3 | Clitheroe v East Lancashire | Chatburn Road, Clitheroe | 2023 |
| 321 | 16 | East Lancashire v Darwen | Alexandra Meadows, Blackburn | 2017 |
| 316 | 6 | East Lancashire v Church | Alexandra Meadows, Blackburn | 2021 |
| 311 | 10 | East Lancashire v Great Harwood | Alexandra Meadows, Blackburn | 2021 |
| 303 | 12 | Enfield v East Lancashire | Dill Hall Lane, Enfield | 2009 |
| 303 | 14 | East Lancashire v Colne | Alexandra Meadows, Blackburn | 2018 |
| 297 | 10 | Haslingden v East Lancashire | Bentgate, Haslingden | 2005 |
| 294 | 14 | Accrington v East Lancashire | Thorneyholme Road, Accrington | 2012 |
| 293 | 15 | Enfield v East Lancashire | Dill Hall Lane, Enfield | 2016 |
| 292 | 12 | Ramsbottom v East Lancashire | Acre Bottom, Ramsbottom | 2017 |
| 291 | 14 | East Lancashire v Accrington | Alexandra Meadows, Blackburn | 2007 |
| 291 | 8 | East Lancashire v Accrington | Alexandra Meadows, Blackburn | 2018 |
| 287 | 20 | Accrington v East Lancashire | Thorneyholme Road, Accrington | 2006 |
| 287 | 13 | Lowerhouse v East Lancashire | The Brooks Foundation Ground, Lowerhouse | 2022 |
| 285 | 14 | East Lancashire v Rishton | Alexandra Meadows, Blackburn | 2019 |
| 284 | 13 | Ramsbottom v East Lancashire | Acre Bottom, Ramsbottom | 2015 |
| 283 | 11 | Rishton v East Lancashire | Blackburn Road, Rishton | 2007 |
| 283 | 9 | Todmorden v East Lancashire | Centre Vale, Todmorden | 2016 |
| 281 | 17 | East Lancashire v Rishton | Alexandra Meadows, Blackburn | 2006 |
| 280 | 15 | Accrington v East Lancashire | Thorneyholme Road, Accrington | 2010 |
| 280 | 9 | Lowerhouse v East Lancashire | Liverpool Road, Lowerhouse | 2017 |
| 280 | 15 | Church v East Lancashire | Blackburn Road, Oswaldtwistle | 2022 |
| 278 | 12 | East Lancashire v Church | Alexandra Meadows, Blackburn | 2024 |
| 277 | 13 | East Lancashire v Enfield | Alexandra Meadows, Blackburn | 2008 |
| 276 | 14 | East Lancashire v Church | Alexandra Meadows, Blackburn | 2009 |
| 276 | 8 | Lowerhouse v East Lancashire | Liverpool Road, Lowerhouse | 2016 |
