| Runs |
Out of |
4s |
6s |
| 76 | 102* | 13 | 4 | | G Clark | Durham v Northamptonshire | County Ground, Northampton | 2023 |
| 62 | 91* | 14 | 1 | | G Clark | Durham v Yorkshire | Headingley, Leeds | 2015 |
| 76 | 101* | 7 | 8 | | AZ Lees | Durham v Northamptonshire | Banks Homes Riverside, Chester-le-Street | 2025 |
| 62 | 91 | 11 | 3 | | P Mustard | Durham v Yorkshire | Emirates Durham International Cricket Ground, Chester-le-Street | 2013 |
| 64 | 108* | 10 | 4 | | PD Collingwood | Durham v Worcestershire | County Ground, New Road, Worcester | 2017 |
| 64 | 79 | 10 | 4 | | G Clark | Durham v Northamptonshire | Banks Homes Riverside, Chester-le-Street | 2025 |
| 70 | 80* | 4 | 9 | | LRPL Taylor | Durham v Leicestershire | Emirates Durham International Cricket Ground, Chester-le-Street | 2010 |
| 56 | 75 | 11 | 2 | | P Mustard | Durham v Nottinghamshire | Emirates Durham International Cricket Ground, Chester-le-Street | 2011 |
| 62 | 90* | 8 | 5 | | BA Stokes | Durham v Yorkshire | Emerald Headingley Cricket Stadium, Leeds | 2018 |
| 60 | 70 | 9 | 4 | | S Steel | Durham v Leicestershire | Fischer County Ground, Grace Road, Leicester | 2019 |
| 54 | 70 | 12 | 1 | | DJM Short | Durham v Leicestershire | Emirates Riverside, Chester-le-Street | 2019 |
| 64 | 83 | 7 | 6 | | CN Ackermann | Durham v Nottinghamshire | Banks Homes Riverside, Chester-le-Street | 2025 |
| 52 | 76 | 10 | 2 | | HH Gibbs | Durham v Yorkshire | Emirates Durham International Cricket Ground, Chester-le-Street | 2012 |
| 54 | 83* | 9 | 3 | | HH Gibbs | Durham v Derbyshire | Emirates Durham International Cricket Ground, Chester-le-Street | 2012 |
| 50 | 54 | 11 | 1 | | P Mustard | Durham v Derbyshire | Emirates Durham International Cricket Ground, Chester-le-Street | 2014 |
| 48 | 60 | 12 | 0 | | CS MacLeod | Durham v Northamptonshire | Emirates Durham International Cricket Ground, Chester-le-Street | 2015 |
| 50 | 68 | 11 | 1 | | DJM Short | Durham v Derbyshire | The Pattonair County Ground, Derby | 2019 |
| 54 | 63 | 9 | 3 | | DG Bedingham | Durham v Warwickshire | Edgbaston, Birmingham | 2024 |
| 56 | 87 | 8 | 4 | | G Clark | Durham v Lancashire | Seat Unique Riverside Ground, Chester-le-Street | 2024 |
| 50 | 77 | 11 | 1 | | AZ Lees | Durham v Nottinghamshire | Banks Homes Riverside, Chester-le-Street | 2025 |
| 48 | 79 | 9 | 2 | | ID Blackwell | Durham v Warwickshire | Edgbaston, Birmingham | 2010 |
| 46 | 65 | 10 | 1 | | P Mustard | Durham v Leicestershire | Emirates Durham International Cricket Ground, Chester-le-Street | 2010 |
| 46 | 61* | 10 | 1 | | P Mustard | Durham v Northamptonshire | County Ground, Northampton | 2011 |
| 48 | 71 | 9 | 2 | | G Clark | Durham v Northamptonshire | County Ground, Northampton | 2017 |
| 50 | 98* | 8 | 3 | | TWM Latham | Durham v Nottinghamshire | Trent Bridge, Nottingham | 2018 |
| 56 | 78 | 5 | 6 | | TWM Latham | Durham v Worcestershire | Blackfinch New Road, Worcester | 2018 |
| 56 | 77* | 5 | 6 | | DJM Short | Durham v Leicestershire | Fischer County Ground, Grace Road, Leicester | 2019 |
| 46 | 78 | 10 | 1 | | AZ Lees | Durham v Lancashire | Emirates Old Trafford, Manchester | 2023 |
| 52 | 78 | 7 | 4 | | DG Bedingham | Durham v Lancashire | Seat Unique Riverside Ground, Chester-le-Street | 2024 |
| 44 | 70 | 11 | 0 | | OG Robinson | Durham v Derbyshire | Banks Homes Riverside, Chester-le-Street | 2025 |
