| 501* | BC Lara | Warwickshire v Durham | Edgbaston, Birmingham | 1994 |
| 424 | AC MacLaren | Lancashire v Somerset | County Ground, Taunton | 1895 |
| 410* | SA Northeast | Glamorgan v Leicestershire | Uptonsteel County Ground, Leicester | 2022 |
| 405* | GA Hick | Worcestershire v Somerset | County Ground, Taunton | 1988 |
| 371 | T Banton | Somerset v Worcestershire | The Cooper Associates County Ground, Taunton | 2025 |
| 366 | NH Fairbrother | Lancashire v Surrey | The Foster's Oval, Kennington | 1990 |
| 357* | R Abel | Surrey v Somerset | Kennington Oval, Kennington | 1899 |
| 355* | KP Pietersen | Surrey v Leicestershire | The Kia Oval, Kennington | 2015 |
| 344* | MW Goodwin | Sussex v Somerset | County Ground, Taunton | 2009 |
| 343* | PA Perrin | Essex v Derbyshire | Queen's Park, Chesterfield | 1904 |
| 342 | JL Langer | Somerset v Surrey | Woodbridge Road, Guildford | 2006 |
| 341 | GH Hirst | Yorkshire v Leicestershire | Aylestone Road, Leicester | 1905 |
| 341 | CM Spearman | Gloucestershire v Middlesex | Archdeacon Meadow, Gloucester | 2004 |
| 339 | DS Lehmann | Yorkshire v Durham | Headingley, Leeds | 2006 |
| 335* | MW Goodwin | Sussex v Leicestershire | County Ground, Hove | 2003 |
| 335* | SA Northeast | Glamorgan v Middlesex | Lord's Cricket Ground, St John's Wood | 2024 |
| 333 | KS Duleepsinhji | Sussex v Northamptonshire | County Ground, Hove | 1930 |
| 332 | WH Ashdown | Kent v Essex | Old County Ground, Brentwood | 1934 |
| 331* | JDB Robertson | Middlesex v Worcestershire | County Ground, New Road, Worcester | 1949 |
| 331* | MEK Hussey | Northamptonshire v Somerset | County Ground, Taunton | 2003 |
| 329* | MEK Hussey | Northamptonshire v Essex | County Ground, Northampton | 2001 |
| 322 | E Paynter | Lancashire v Sussex | County Ground, Hove | 1937 |
| 322 | IVA Richards | Somerset v Warwickshire | County Ground, Taunton | 1985 |
| 322* | MB Loye | Northamptonshire v Glamorgan | County Ground, Northampton | 1998 |
| 319 | CJL Rogers | Northamptonshire v Gloucestershire | County Ground, Northampton | 2006 |
| 318 | SR Dickson | Kent v Northamptonshire | The Kent County Cricket Ground, Beckenham | 2017 |
| 318 | KK Jennings | Lancashire v Somerset | Trafalgar Road, Southport | 2022 |
| 317 | WR Hammond | Gloucestershire v Nottinghamshire | Wagon Works Ground, Gloucester | 1936 |
| 316* | JB Hobbs | Surrey v Middlesex | Lord's Cricket Ground, St John's Wood | 1926 |
| 316 | RH Moore | Hampshire v Warwickshire | Dean Park, Bournemouth | 1937 |
| 315* | TW Hayward | Surrey v Lancashire | Kennington Oval, Kennington | 1898 |
| 315* | P Holmes | Yorkshire v Middlesex | Lord's Cricket Ground, St John's Wood | 1925 |
| 315 | MA Wagh | Warwickshire v Middlesex | Lord's Cricket Ground, St John's Wood | 2001 |
| 315* | GA Hick | Worcestershire v Durham | County Ground, New Road, Worcester | 2002 |
| 315 | JL Langer | Somerset v Middlesex | County Ground, Taunton | 2007 |
| 313 | H Sutcliffe | Yorkshire v Essex | County Ground, Leyton | 1932 |
| 313* | SJ Cook | Somerset v Glamorgan | Sophia Gardens, Cardiff | 1990 |
| 313* | DL Lloyd | Glamorgan v Derbyshire | Sophia Gardens, Cardiff | 2022 |
| 312* | WW Keeton | Nottinghamshire v Middlesex | Kennington Oval, Kennington | 1939 |
| 312 | JER Gallian | Lancashire v Derbyshire | Old Trafford, Manchester | 1996 |
| 311 | JT Brown | Yorkshire v Sussex | Bramall Lane, Sheffield | 1897 |
| 311* | GM Turner | Worcestershire v Warwickshire | County Ground, New Road, Worcester | 1982 |
| 311 | GC Smith | Somerset v Leicestershire | County Ground, Taunton | 2005 |
| 311* | JP Crawley | Hampshire v Nottinghamshire | The Rose Bowl, Southampton | 2005 |
| 310 | H Gimblett | Somerset v Sussex | The Saffrons, Eastbourne | 1948 |
| 310* | MEK Hussey | Northamptonshire v Gloucestershire | The Royal and Sun Alliance County Ground, Bristol | 2002 |
| 309* | SP James | Glamorgan v Sussex | Penrhyn Avenue, Rhos-on-Sea, Colwyn Bay | 2000 |
| 309* | HD Ackerman | Leicestershire v Glamorgan | Sophia Gardens, Cardiff | 2006 |
| 305* | FR Foster | Warwickshire v Worcestershire | Tipton Road, Dudley | 1914 |
| 305* | WH Ashdown | Kent v Derbyshire | Crabble Athletic Ground, Dover | 1935 |
| 305 | DP Sibley | Surrey v Durham | The Kia Oval, Kennington | 2025 |
| 304 | RM Poore | Hampshire v Somerset | County Ground, Taunton | 1899 |
| 303* | GA Hick | Worcestershire v Hampshire | County Ground, Southampton | 1997 |
| 303* | DJG Sales | Northamptonshire v Essex | County Ground, Northampton | 1999 |
| 303* | NV Knight | Warwickshire v Middlesex | Lord's Cricket Ground, St John's Wood | 2004 |
| 303* | JC Hildreth | Somerset v Warwickshire | County Ground, Taunton | 2009 |
| 302* | P Holmes | Yorkshire v Hampshire | United Services Ground, Portsmouth | 1920 |
| 302* | WR Hammond | Gloucestershire v Glamorgan | Ashley Down Ground, Bristol | 1934 |
| 302 | WR Hammond | Gloucestershire v Glamorgan | Rodney Parade, Newport | 1939 |
| 302* | BJ Hodge | Leicestershire v Nottinghamshire | Trent Bridge, Nottingham | 2003 |
| 301 | WG Grace | Gloucestershire v Sussex | Ashley Down Ground, Bristol | 1896 |
| 301* | EH Hendren | Middlesex v Worcestershire | Tipton Road, Dudley | 1933 |
| 301* | JP Crawley | Hampshire v Nottinghamshire | Trent Bridge, Nottingham | 2004 |
| 301* | MR Ramprakash | Surrey v Northamptonshire | The Brit Oval, Kennington | 2006 |
| 300 | JT Brown | Yorkshire v Derbyshire | Queen's Park, Chesterfield | 1898 |
| 300* | FB Watson | Lancashire v Surrey | Old Trafford, Manchester | 1928 |
| 300 | R Subba Row | Northamptonshire v Surrey | Kennington Oval, Kennington | 1958 |
| 300* | MA Carberry | Hampshire v Yorkshire | The Rose Bowl, Southampton | 2011 |
| 300* | DJ Bell-Drummond | Kent v Northamptonshire | County Ground, Northampton | 2023 |
| 299 | MJ Powell | Glamorgan v Gloucestershire | College Ground, Cheltenham | 2006 |
| 298 | DKH Mitchell | Worcestershire v Somerset | County Ground, Taunton | 2009 |
| 297 | MJ Wood | Somerset v Yorkshire | County Ground, Taunton | 2005 |
| 296 | AO Jones | Nottinghamshire v Gloucestershire | Trent Bridge, Nottingham | 1903 |
| 295* | JT Tyldesley | Lancashire v Kent | Old Trafford, Manchester | 1906 |
| 295 | LEG Ames | Kent v Gloucestershire | Cheriton Road Sports Ground, Folkestone | 1933 |
| 295* | AD Brown | Surrey v Leicestershire | Doncaster Close, Oakham School | 2000 |
| 294 | JR Gunn | Nottinghamshire v Leicestershire | Trent Bridge, Nottingham | 1903 |
| 294* | DM Ward | Surrey v Derbyshire | The Foster's Oval, Kennington | 1994 |
| 292 | LCH Palairet | Somerset v Hampshire | County Ground, Southampton | 1896 |
| 292* | A Sandham | Surrey v Northamptonshire | Kennington Oval, Kennington | 1921 |
| 292 | MR Ramprakash | Surrey v Gloucestershire | The Brit Oval, Kennington | 2006 |
| 291 | E Paynter | Lancashire v Hampshire | County Ground, Southampton | 1938 |
| 291 | IA Greig | Surrey v Lancashire | The Foster's Oval, Kennington | 1990 |
| 291 | JWA Taylor | Nottinghamshire v Sussex | Cricket Field Road, Horsham | 2015 |
| 290* | A Ducat | Surrey v Essex | County Ground, Leyton | 1921 |
| 290 | WR Hammond | Gloucestershire v Kent | The Nevill Ground, Tunbridge Wells | 1934 |
| 288 | WG Grace | Gloucestershire v Somerset | Ashley Down Ground, Bristol | 1895 |
| 287* | DE Davies | Glamorgan v Gloucestershire | Rodney Parade, Newport | 1939 |
| 286 | GL Jessop | Gloucestershire v Sussex | County Ground, Hove | 1903 |
| 286 | JR Freeman | Essex v Northamptonshire | County Ground, Northampton | 1921 |
| 286 | AN Petersen | Lancashire v Glamorgan | Penrhyn Avenue, Rhos-on-Sea, Colwyn Bay | 2015 |
| 285* | KS Ranjitsinhji | Sussex v Somerset | County Ground, Taunton | 1901 |
| 285* | JW Hearne | Middlesex v Essex | County Ground, Leyton | 1929 |
| 285 | P Holmes | Yorkshire v Nottinghamshire | Trent Bridge, Nottingham | 1929 |
| 285 | JH Wharton | Yorkshire v Northamptonshire | Headingley, Leeds | 2024 |
| 284 | ME Trescothick | Somerset v Northamptonshire | County Ground, Northampton | 2007 |
| 283 | EH Bowley | Sussex v Middlesex | County Ground, Hove | 1933 |
| 282* | A Sandham | Surrey v Lancashire | Old Trafford, Manchester | 1928 |
| 282* | BM Duckett | Northamptonshire v Sussex | County Ground, Northampton | 2016 |
| 281* | JP Crawley | Lancashire v Somerset | Trafalgar Road, Southport | 1994 |
| 280* | CP Mead | Hampshire v Nottinghamshire | County Ground, Southampton | 1921 |
| 280* | EH Bowley | Sussex v Gloucestershire | County Ground, Hove | 1929 |
| 280* | RG Duckfield | Glamorgan v Surrey | Kennington Oval, Kennington | 1936 |
| 280* | L Hutton | Yorkshire v Hampshire | Bramall Lane, Sheffield | 1939 |
| 280 | JP Crawley | Lancashire v Northamptonshire | Old Trafford, Manchester | 2001 |
| 279* | MR Ramprakash | Surrey v Nottinghamshire | Whitgift School, Croydon | 2003 |
| 279 | DG Bedingham | Durham v Lancashire | Seat Unique Riverside Ground, Chester-le-Street | 2024 |
| 278 | TER Cook | Sussex v Hampshire | County Ground, Hove | 1930 |
| 277 | CP McGahey | Essex v Derbyshire | County Ground, Leyton | 1905 |
| 277* | P Holmes | Yorkshire v Northamptonshire | St George's Road, Harrogate | 1921 |
| 277* | EH Hendren | Middlesex v Kent | Lord's Cricket Ground, St John's Wood | 1922 |
| 277* | TF Shepherd | Surrey v Gloucestershire | Kennington Oval, Kennington | 1927 |
| 277* | RG Twose | Warwickshire v Glamorgan | Edgbaston, Birmingham | 1994 |
| 277 | RA White | Northamptonshire v Gloucestershire | County Ground, Northampton | 2002 |
| 277* | CN Ackermann | Leicestershire v Sussex | The 1st Central County Ground, Hove | 2022 |
| 276 | EG Hayes | Surrey v Hampshire | Kennington Oval, Kennington | 1909 |
| 276 | FL Bowley | Worcestershire v Hampshire | Tipton Road, Dudley | 1914 |
| 276 | DJG Sales | Northamptonshire v Nottinghamshire | County Ground, Northampton | 2000 |
| 275 | KS Ranjitsinhji | Sussex v Leicestershire | Grace Road, Leicester | 1900 |
| 275 | P Holmes | Yorkshire v Warwickshire | Park Avenue Cricket Ground, Bradford | 1928 |
| 275 | GA Gooch | Essex v Kent | County Ground, Chelmsford | 1988 |
| 275* | MJ Walker | Kent v Somerset | St Lawrence Ground, Canterbury | 1996 |
| 275 | DJ Hussey | Nottinghamshire v Essex | Trent Bridge, Nottingham | 2007 |
| 275* | AZ Lees | Yorkshire v Derbyshire | Queen's Park, Chesterfield | 2013 |
