Most Runs in a Season for Sydney Sixers
| 537 | JM Vince | 2020/21 |
| 508 | JR Philippe | 2020/21 |
| 487 | JR Philippe | 2019/20 |
| 440 | MC Henriques | 2021/22 |
| 429 | JR Philippe | 2021/22 |
| 399 | DP Hughes | 2018/19 |
| 382 | JC Silk | 2020/21 |
| 363 | JC Silk | 2022/23 |
| 362 | MJ Lumb | 2012/13 |
| 346 | SPD Smith | 2022/23 |
| 331 | DP Hughes | 2020/21 |
| 323 | JM Vince | 2019/20 |
| 319 | BJ Haddin | 2012/13 |
| 306 | MC Henriques | 2022/23 |
| 304 | DP Hughes | 2016/17 |
| 304 | JR Philippe | 2018/19 |
| 291 | NJ Maddinson | 2017/18 |
| 289 | MC Henriques | 2018/19 |
| 287 | DP Hughes | 2021/22 |
| 284 | NJ Maddinson | 2014/15 |
| 280 | JC Silk | 2018/19 |
| 275 | NJ Maddinson | 2011/12 |
| 272 | JC Silk | 2014/15 |
| 272 | DT Christian | 2020/21 |
| 269 | JM Vince | 2018/19 |
| 267 | DP Hughes | 2019/20 |
| 267 | MC Henriques | 2019/20 |
| 266 | JR Philippe | 2022/23 |
| 265 | MJ Lumb | 2014/15 |
| 264 | SPD Smith | 2012/13 |
| 264 | DT Christian | 2021/22 |
| 263 | MC Henriques | 2016/17 |
| 263 | JM Vince | 2022/23 |
| 257 | MC Henriques | 2023/24 |
| 257 | JR Philippe | 2023/24 |
| 253 | MJ Lumb | 2015/16 |
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