| Runs |
Out of |
4s |
6s |
| 58 | 96 | 7 | 5 | | Samiullah Shenwari | Afghanistan v Scotland | University Oval, Dunedin | 2014/15 |
| 56 | 80 | 8 | 4 | | Rahmanullah Gurbaz | Afghanistan v England | Feroz Shah Kotla, Delhi | 2023/24 |
| 50 | 129* | 8 | 3 | | Ibrahim Zadran | Afghanistan v Australia | Wankhede Stadium, Mumbai | 2023/24 |
| 44 | 56 | 8 | 2 | | Najibullah Zadaran | Afghanistan v New Zealand | McLean Park, Napier | 2014/15 |
| 40 | 62 | 10 | 0 | | Rahmat Shah | Afghanistan v West Indies | Emerald Headingley Cricket Stadium, Leeds | 2019 |
| 40 | 87 | 10 | 0 | | Ibrahim Zadran | Afghanistan v Pakistan | MA Chidambaram Stadium, Chepauk, Chennai | 2023/24 |
| 42 | 65 | 9 | 1 | | Rahmanullah Gurbaz | Afghanistan v Pakistan | MA Chidambaram Stadium, Chepauk, Chennai | 2023/24 |
| 46 | 97* | 7 | 3 | | Azmatullah Omarzai | Afghanistan v South Africa | Narendra Modi Stadium, Motera, Ahmedabad | 2023/24 |
| 40 | 51 | 7 | 2 | | Najibullah Zadaran | Afghanistan v Australia | County Ground, Bristol | 2019 |
| 36 | 59 | 9 | 0 | | Hashmatullah Shahidi | Afghanistan v New Zealand | The Cooper Associates County Ground, Taunton | 2019 |
| 38 | 80 | 8 | 1 | | Hashmatullah Shahidi | Afghanistan v India | Feroz Shah Kotla, Delhi | 2023/24 |
| 42 | 73* | 6 | 3 | | Azmatullah Omarzai | Afghanistan v Sri Lanka | Maharashtra Cricket Association Stadium, Gahunje | 2023/24 |
| 32 | 51 | 8 | 0 | | Javed Ahmadi | Afghanistan v Scotland | University Oval, Dunedin | 2014/15 |
| 32 | 86 | 8 | 0 | | Ikram Alikhil | Afghanistan v West Indies | Emerald Headingley Cricket Stadium, Leeds | 2019 |
| 32 | 52 | 8 | 0 | | Rahmat Shah | Afghanistan v Netherlands | Bharat Ratna Shri Atal Bihari Vajpayee Ekana Cricket Stadium, Lucknow | 2023/24 |
| 32 | 76 | 5 | 2 | | Hashmatullah Shahidi | Afghanistan v England | Emirates Old Trafford, Manchester | 2019 |
| 32 | 77* | 5 | 2 | | Rahmat Shah | Afghanistan v Pakistan | MA Chidambaram Stadium, Chepauk, Chennai | 2023/24 |
| 28 | 62 | 7 | 0 | | Rahmat Shah | Afghanistan v Sri Lanka | Maharashtra Cricket Association Stadium, Gahunje | 2023/24 |
| 26 | 54 | 5 | 1 | | Asghar Stanikzai | Afghanistan v Sri Lanka | University Oval, Dunedin | 2014/15 |
| 26 | 54 | 5 | 1 | | Samiullah Shenwari | Afghanistan v New Zealand | McLean Park, Napier | 2014/15 |
| 24 | 43 | 6 | 0 | | Rahmat Shah | Afghanistan v Australia | County Ground, Bristol | 2019 |
| 24 | 43 | 6 | 0 | | Najibullah Zadaran | Afghanistan v Sri Lanka | Sophia Gardens, Cardiff | 2019 |
| 26 | 34 | 5 | 1 | | Hazratullah Zazai | Afghanistan v New Zealand | The Cooper Associates County Ground, Taunton | 2019 |
| 24 | 35 | 6 | 0 | | Rashid Khan | Afghanistan v South Africa | Sophia Gardens, Cardiff | 2019 |
| 24 | 42 | 6 | 0 | | Najibullah Zadaran | Afghanistan v Pakistan | Emerald Headingley Cricket Stadium, Leeds | 2019 |
| 32 | 62 | 2 | 4 | | Azmatullah Omarzai | Afghanistan v India | Feroz Shah Kotla, Delhi | 2023/24 |
| 24 | 56* | 6 | 0 | | Hashmatullah Shahidi | Afghanistan v Netherlands | Bharat Ratna Shri Atal Bihari Vajpayee Ekana Cricket Stadium, Lucknow | 2023/24 |
| 20 | 44 | 5 | 0 | | Mohammad Nabi | Afghanistan v Bangladesh | Manuka Oval, Canberra | 2014/15 |
| 20 | 38 | 5 | 0 | | Samiullah Shenwari | Afghanistan v Sri Lanka | University Oval, Dunedin | 2014/15 |
| 22 | 31 | 4 | 1 | | Gulbadeen Naib | Afghanistan v Australia | County Ground, Bristol | 2019 |
| 26 | 27 | 2 | 3 | | Rashid Khan | Afghanistan v Australia | County Ground, Bristol | 2019 |
| 20 | 31 | 5 | 0 | | Noor Ali Zadran | Afghanistan v New Zealand | The Cooper Associates County Ground, Taunton | 2019 |
| 24 | 44 | 3 | 2 | | Asghar Stanikzai | Afghanistan v England | Emirates Old Trafford, Manchester | 2019 |
| 22 | 37 | 4 | 1 | | Gulbadeen Naib | Afghanistan v England | Emirates Old Trafford, Manchester | 2019 |
| 22 | 52 | 4 | 1 | | Mohammad Nabi | Afghanistan v India | The Ageas Bowl, Southampton | 2019 |
| 24 | 42 | 3 | 2 | | Asghar Stanikzai | Afghanistan v Pakistan | Emerald Headingley Cricket Stadium, Leeds | 2019 |
| 20 | 35 | 5 | 0 | | Rahmat Shah | Afghanistan v Pakistan | Emerald Headingley Cricket Stadium, Leeds | 2019 |
| 22 | 40 | 4 | 1 | | Asghar Stanikzai | Afghanistan v West Indies | Emerald Headingley Cricket Stadium, Leeds | 2019 |
| 22 | 47 | 4 | 1 | | Rahmanullah Gurbaz | Afghanistan v Bangladesh | Himachal Pradesh Cricket Association Stadium, Dharamsala | 2023/24 |
| 24 | 58 | 3 | 2 | | Ikram Alikhil | Afghanistan v England | Feroz Shah Kotla, Delhi | 2023/24 |
| 22 | 39 | 4 | 1 | | Ibrahim Zadran | Afghanistan v Sri Lanka | Maharashtra Cricket Association Stadium, Gahunje | 2023/24 |
| 26 | 35* | 2 | 3 | | Rashid Khan | Afghanistan v Australia | Wankhede Stadium, Mumbai | 2023/24 |
