| inns & 378 runs | v Sussex | Trent Bridge, Nottingham | 1895 | f4207 |
| inns & 327 runs | v Glamorgan | Trent Bridge, Nottingham | 1929 | f12776 |
| inns & 294 runs | v Sussex | Trent Bridge, Nottingham | 1887 | f3194 |
| inns & 289 runs | v Sussex | County Ground, Hove | 1887 | f3168 |
| inns & 281 runs | v Kent | Trent Bridge, Nottingham | 1869 | f1559 |
| inns & 280 runs | v Leicestershire | Trent Bridge, Nottingham | 2017 | f57933 |
| inns & 267 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 1932 | f13825 |
| inns & 266 runs | v Sussex | Trent Bridge, Nottingham | 1890 | f3464 |
| inns & 256 runs | v Gloucestershire | Trent Bridge, Nottingham | 1903 | f6177 |
| inns & 250 runs | v Derbyshire | County Ground, Derby | 1885 | f2947 |
| inns & 241 runs | v Hampshire | Trent Bridge, Nottingham | 1935 | f14943 |
| inns & 229 runs | v Northamptonshire | County Ground, Northampton | 1906 | f6864 |
| inns & 219 runs | v Essex | Trent Bridge, Nottingham | 1908 | f7423 |
| inns & 207 runs | v Durham University Centre of Cricketing Excellence | The Racecourse, Durham | 2006 | f49357 |
| inns & 205 runs | v Glamorgan | Trent Bridge, Nottingham | 1922 | f10162 |
| inns & 199 runs | v Australians | Trent Bridge, Nottingham | 1888 | f3316 |
| inns & 190 runs | v Kent | Bat and Ball Ground, Gravesend | 1928 | f12302 |
| inns & 190 runs | v Middlesex | Kennington Oval, Kennington | 1939 | f16615 |
| inns & 189 runs | v Surrey | Kennington Oval, Kennington | 1882 | f2548 |
| inns & 180 runs | v Kent | St Lawrence Ground, Canterbury | 1879 | f2205 |
| inns & 180 runs | v Derbyshire | Trent Bridge, Nottingham | 1899 | f5125 |
| inns & 177 runs | v Kent | Swifts Park, Cranbrook | 1863 | f1240 |
| inns & 175 runs | v Sussex | County Ground, Hove | 1919 | f9350 |
| inns & 172 runs | v Essex | Trent Bridge, Nottingham | 1905 | f6570 |
| inns & 170 runs | v Surrey | Trent Bridge, Nottingham | 1909 | f7673 |
| inns & 170 runs | v Worcestershire | Trent Bridge, Nottingham | 2021 | f60433 |
| inns & 169 runs | v Warwickshire | Trent Bridge, Nottingham | 1978 | f32076 |
| inns & 168 runs | v Durham University Centre of Cricketing Excellence | Trent Bridge, Nottingham | 2003 | f47229 |
| inns & 162 runs | v Somerset | Trent Bridge, Nottingham | 1932 | f13854 |
| inns & 160 runs | v Somerset | The Cooper Associates County Ground, Taunton | 2021 | f60487 |
| inns & 159 runs | v Derbyshire | Welbeck Abbey Estate Cricket Ground, Welbeck Abbey | 1901 | f5683 |
| inns & 157 runs | v Durham | Ropery Lane, Chester-le-Street | 1993 | f40659 |
| inns & 156 runs | v Glamorgan | Trent Bridge, Nottingham | 1932 | f14031 |
| inns & 155 runs | v Gloucestershire | Ashley Down Ground, Bristol | 1911 | f8224 |
| inns & 155 runs | v Leicestershire | Aylestone Road, Leicester | 1925 | f11221 |
| inns & 154 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1885 | f2914 |
| inns & 154 runs | v Leicestershire | Trent Bridge, Nottingham | 1920 | f9567 |
| inns & 153 runs | v Surrey | Trent Bridge, Nottingham | 1889 | f3372 |
| inns & 151 runs | v Sussex | Trent Bridge, Nottingham | 1884 | f2722 |
| inns & 151 runs | v Warwickshire | Trent Bridge, Nottingham | 2005 | f48773 |