| inns & 378 runs | v Sussex | Trent Bridge, Nottingham | 1895 | f4209 |
| inns & 327 runs | v Glamorgan | Trent Bridge, Nottingham | 1929 | f12780 |
| inns & 294 runs | v Sussex | Trent Bridge, Nottingham | 1887 | f3196 |
| inns & 289 runs | v Sussex | County Ground, Hove | 1887 | f3170 |
| inns & 281 runs | v Kent | Trent Bridge, Nottingham | 1869 | f1560 |
| inns & 280 runs | v Leicestershire | Trent Bridge, Nottingham | 2017 | f57937 |
| inns & 267 runs | v Cambridge University | FP Fenner's Ground, Cambridge | 1932 | f13829 |
| inns & 266 runs | v Sussex | Trent Bridge, Nottingham | 1890 | f3466 |
| inns & 256 runs | v Gloucestershire | Trent Bridge, Nottingham | 1903 | f6179 |
| inns & 250 runs | v Derbyshire | County Ground, Derby | 1885 | f2949 |
| inns & 241 runs | v Hampshire | Trent Bridge, Nottingham | 1935 | f14947 |
| inns & 229 runs | v Northamptonshire | County Ground, Northampton | 1906 | f6866 |
| inns & 219 runs | v Essex | Trent Bridge, Nottingham | 1908 | f7427 |
| inns & 207 runs | v Durham University Centre of Cricketing Excellence | The Racecourse, Durham | 2006 | f49361 |
| inns & 205 runs | v Glamorgan | Trent Bridge, Nottingham | 1922 | f10166 |
| inns & 199 runs | v Australians | Trent Bridge, Nottingham | 1888 | f3318 |
| inns & 190 runs | v Kent | Bat and Ball Ground, Gravesend | 1928 | f12306 |
| inns & 190 runs | v Middlesex | Kennington Oval, Kennington | 1939 | f16619 |
| inns & 189 runs | v Surrey | Kennington Oval, Kennington | 1882 | f2550 |
| inns & 180 runs | v Kent | St Lawrence Ground, Canterbury | 1879 | f2207 |
| inns & 180 runs | v Derbyshire | Trent Bridge, Nottingham | 1899 | f5127 |
| inns & 177 runs | v Kent | Swifts Park, Cranbrook | 1863 | f1240 |
| inns & 175 runs | v Sussex | County Ground, Hove | 1919 | f9354 |
| inns & 172 runs | v Essex | Trent Bridge, Nottingham | 1905 | f6572 |
| inns & 170 runs | v Surrey | Trent Bridge, Nottingham | 1909 | f7677 |
| inns & 170 runs | v Worcestershire | Trent Bridge, Nottingham | 2021 | f60437 |
| inns & 169 runs | v Warwickshire | Trent Bridge, Nottingham | 1978 | f32080 |
| inns & 168 runs | v Durham University Centre of Cricketing Excellence | Trent Bridge, Nottingham | 2003 | f47233 |
| inns & 162 runs | v Somerset | Trent Bridge, Nottingham | 1932 | f13858 |
| inns & 160 runs | v Somerset | The Cooper Associates County Ground, Taunton | 2021 | f60491 |
| inns & 159 runs | v Derbyshire | Welbeck Abbey Estate Cricket Ground, Welbeck Abbey | 1901 | f5685 |
| inns & 157 runs | v Durham | Ropery Lane, Chester-le-Street | 1993 | f40663 |
| inns & 156 runs | v Glamorgan | Trent Bridge, Nottingham | 1932 | f14035 |
| inns & 155 runs | v Gloucestershire | Ashley Down Ground, Bristol | 1911 | f8228 |
| inns & 155 runs | v Leicestershire | Aylestone Road, Leicester | 1925 | f11225 |
| inns & 154 runs | v Middlesex | Lord's Cricket Ground, St John's Wood | 1885 | f2916 |
| inns & 154 runs | v Leicestershire | Trent Bridge, Nottingham | 1920 | f9571 |
| inns & 153 runs | v Surrey | Trent Bridge, Nottingham | 1889 | f3374 |
| inns & 151 runs | v Sussex | Trent Bridge, Nottingham | 1884 | f2724 |
| inns & 151 runs | v Warwickshire | Trent Bridge, Nottingham | 2005 | f48777 |