| 129* | AJ Lamb | Northamptonshire v Middlesex | 1994 | a8712 |
| 120* | EJG Morgan | Middlesex v Worcestershire | 2012 | a22078 |
| 107 | NRD Compton | Middlesex v Derbyshire | 2009 | a19964 |
| 104 | MR Ramprakash | Middlesex v Surrey | 1990 | a6641 |
| 103* | KR Brown | Middlesex v Surrey | 1990 | a6641 |
| 103 | MR Ramprakash | Middlesex v Northamptonshire | 1995 | a9406 |
| 100 | MA Lynch | Gloucestershire v Middlesex | 1997 | a10607 |
| 100 | JH Kallis | Middlesex v Gloucestershire | 1997 | a10607 |
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