Largest Margin of Runs Defeat
| 160 runs | by Gauteng | Imperial Wanderers Stadium, Johannesburg | 2021/22 | a28895 |
| 152 runs | by Transvaal | New Wanderers Stadium, Johannesburg | 1983/84 | a3913 |
| 142 runs | by Northerns | Pollock Field, Grey High School Ground, Port Elizabeth | 2013/14 | a23052 |
| 135 runs | by South Western Districts | Recreation Ground, Oudtshoorn | 2010/11 | a21068 |
| 125 runs | by Easterns | Sahara Park Willowmoore, Benoni | 2017/18 | a25842 |
| 124 runs | by Transvaal | New Wanderers Stadium, Johannesburg | 1982/83 | a3502 |
| 123 runs | by Natal | St George's Park, Port Elizabeth | 1985/86 | a4635 |
| 119 runs | by Gauteng | St George's Park, Port Elizabeth | 2015/16 | a24651 |
| 116 runs | by Western Province | Newlands, Cape Town | 1970/71 | a456 |
| 113 runs | by Orange Free State | Springbok Park, Bloemfontein | 1994/95 | a9170 |
| 111 runs | by Northerns | SuperSport Park, Centurion | 2024/25 | a31562 |
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